Results 61 to 70 of about 792 (145)

Effect of Adding Bifidobacterium animalis BZ25 on the Flavor, Functional Components and Biogenic Amines of Natto by Bacillus subtilis GUTU09

Foods, 2022
Natto is a high-value fermented soybean produced by B. subtilis. However, B. subtilis produces a pungent amine odor. This study compared the volatile organic compounds (VOCs), free amino acids (FAAs) and biogenic amines (BAs), nattokinase (NK) of natto ...
Qifeng Zhang, Guangqun Lan, Xueyi Tian, Laping He, Cuiqin Li, Han Tao, Xuefeng Zeng, Xiao Wang   +7 more
doaj   +1 more source

Revisiting Cholesterol‐Lowering Nutraceuticals and Functional Foods: Mechanistic Insights Into Cholesterol Homeostasis and Gut Microbiota

Food Chemistry International, Volume 1, Issue 3, Page 265-293, September 2025.
Mechanistic Insights into Cholesterol Homeostasis and Gut Microbiota. ABSTRACT The gut microbiota acts as a crucial intermediary between diets and human health. The accumulating evidence suggests that gut microbiota may play a significant role in cholesterol metabolism.
Xiaoxuan Zhang, Huafang Ding, Wensen He, Shouhe Huang, Lin Lei   +4 more
wiley   +1 more source

PENGARUH NATTOKINASE TERHADAP DAYA KERJA Metformin HCl DALAM MENURUNKAN KADAR GLUKOSA DARAH PADA TIKUS PUTIH JANTAN (Rattus norvegicus) GALUR WISTAR

Pharmaciana, 2013
Interaction of modern drug and traditional drug is an issue that needs to be examined, not least in the treatment of diabetes mellitus. Nattokinase is a nutraceutical product that can be used in conjunction with antidiabetic oral drugs that allows the
M Sandila Okta, Vivi Sofia
doaj   +1 more source

Computation of Protein Thermostability and Epistasis

WIREs Computational Molecular Science, Volume 15, Issue 5, September/October 2025.
Conceptual illustration of computational prediction of protein thermostability and mutational epistasis. A neural network algorithm models changes in heat‐induced (un)folding by correlating sequence mutations with variations in free energy. The nonadditive nature of epistatic mutations is metaphorically represented by Orwell's infamous quote from ...
Francesca Peccati, Cristina M. Segovia, Reyes Núñez‐Franco, Gonzalo Jiménez‐Osés   +3 more
wiley   +1 more source

Adjusting Cell‐Surface Interactions Through a Covalent Immobilization of Biomolecules

Advanced Materials Interfaces, Volume 12, Issue 14, July 25, 2025.
This review presents an overview of current and emerging immobilization techniques coupled with an in‐depth investigation of the underlying mechanisms governing the activity and stability of covalently immobilized biomolecules. The aim of this study is to serve as a guide for the development of long‐lasting biomedical coatings with versatile biological
Sara Shakibania, Manus J. P. Biggs, Katarzyna Krukiewicz   +2 more
wiley   +1 more source

A Sandwich Enzyme-linked Immunosorbent Assay for Nattokinase [PDF]

Bioscience, Biotechnology, and Biochemistry, 1994
A specific and sensitive enzyme-linked immunosorbent assay (ELISA) was developed for nattokinase, a subtilisin-like fibrinolytic enzyme in the fermented soybean food, natto. The assay method was developed using a combination of a murine anti-nattokinase monoclonal antibody coated on the microtiter well as a catching antibody and rabbit anti-nattokinase
Yoshikazu Yuki, Tomoyo Nakagawa, Mitsugu Fujita, Aki Asada, Koichiro Nakanishi, Kazuo Kato   +5 more
openaire   +1 more source

Beating Cardiac Cell Cultures From Different Developmental Stages of Rainbow Trout as a Novel Approach for Replication of Cardiac Fish Viruses

Journal of Fish Diseases, Volume 48, Issue 5, May 2025.
ABSTRACT Piscine orthoreovirus‐1 and 3 (PRV‐1, PRV‐3) cause highly prevalent infection in cultured salmonids and can induce heart and skeletal muscle inflammation (HSMI) resulting in economic losses in aquaculture. However, to date, PRV‐1 and PRV‐3 have withstood replication in continuous cell lines.
Torben Krebs, Julia Bauer, Sarah Graff, Lukas Teich, Markus Sterneberg, Marina Gebert, Henrike Seibel, Bettina Seeger, John Hellmann, Øystein Wessel, Espen Rimstad, Win Surachetpong, Dieter Steinhagen, Verena Jung‐Schroers, Mikolaj Adamek   +14 more
wiley   +1 more source

Safety evaluation of the food enzyme acetolactate decarboxylase from the genetically modified Bacillus subtilis strain DP‐Ezz65

EFSA Journal, Volume 23, Issue 5, May 2025.
Abstract The food enzyme acetolactate decarboxylase (α‐acetolactate decarboxylase; EC 4.1.1.5) is produced with the genetically modified Bacillus subtilis strain DP‐Ezz65 by Genencor International B.V. The genetic modifications do not give rise to safety concerns. The production strain meets the requirements for the qualified presumption of safety (QPS)
EFSA Panel on Food Enzymes (FEZ), Holger Zorn, José Manuel Barat Baviera, Claudia Bolognesi, Francesco Catania, Gabriele Gadermaier, Ralf Greiner, Baltasar Mayo, Alicja Mortensen, Yrjö Henrik Roos, Marize L. M. Solano, Monika Sramkova, Henk Van Loveren, Laurence Vernis, Magdalena Andryszkiewicz, Daniele Cavanna, Cristina Fernàndez‐Fraguas, Silvia Peluso, Yi Liu   +18 more
wiley   +1 more source

Replicating Dynamic Immune Responses at Single‐Cell Resolution within a Microfluidic Human Skin Equivalent

Advanced Science, Volume 12, Issue 10, March 13, 2025.
This study describes the development of a vascularized microfluidic skin equivalent, which supports the delivery of circulating immune cells and replication of dynamic inflammatory responses. Single‐cell transcriptomic analyses provide in depth molecular characterization of the model and insight into the underlying regulatory mechanisms involved in ...
Sarah A. Hindle, Holly Bachas Brook, Alexandra Chrysanthou, Emma S. Chambers, Matthew P. Caley, John T. Connelly   +5 more
wiley   +1 more source

Liposomes as sustainable delivery systems in food, cosmetic, and pharmaceutical applications

Journal of the American Oil Chemists' Society, Volume 102, Issue 3, Page 547-568, March 2025.
Overview of liposome preparation methods and applications. Abstract Liposomes are artificial microscopic vesicles composed of phospholipid bilayers with the ability to encapsulate both hydrophobic and hydrophilic molecules, owing to the amphipathic nature of lipids.
Minfang Luo, B. Dave Oomah, Winifred Akoetey, Yuqing Zhang, Hamed Daneshfozoun, Farah Hosseinian   +5 more
wiley   +1 more source