Results 41 to 50 of about 369,030 (264)

Effects of weathering on mechanical and morphological properties cork filled green polyethylene eco-composites [PDF]

Polímeros, 2020
This study aims to evaluate the effects of natural weathering in the city of Teresina, State of Piauí, Brazil, on the morphology and mechanical properties of eco-composites based on high-density green polyethylene, powdered cork and compatibilizer ...
Gabriela Celso Melo Soares de Vasconcelos, Laura Hecker de Carvalho, Renata Barbosa, Rita de Cássia de Lima Idalino, Tatianny Soares Alves   +4 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Effect of Aging Process on Microstructure Evolution and Mechanical Properties of UFG Zn-22Al Alloy [PDF]

Iranian Journal of Materials Science and Engineering, 2023
Microstructure evolution and mechanical properties of Zn-22Al alloy after post-ECAP natural/artificial aging were investigated. A homogenization treatment was applied to the casting samples.
Bahram Azad, Ali Reza Eivani, Mohammad Taghi Salehi   +2 more
doaj  

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

The Natural Aging Effect on Hardenability in Al-Mg-Si: A Complex Interaction between Composition and Heat Treatment Parameters

Metals, 2018
The technological relevance of Al-Mg-Si alloys has been rapidly growing over the last decade. Of particular interest to current and future applications is the problematic negative effect of prior natural aging on subsequent artificial age hardening.
Alex Poznak, Violet Thole, Paul Sanders
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Modification of AOP-48 Ed. 2 extrapolation expression by introduction of real storage t-T conditions of naturally aged nitrocellulose gun powder [PDF]

Scientific Technical Review, 2019
Comparison of the results of gunpowder chemical stability assessment by procedures based on natural and accelerated aging was performed. It was achieved by introducing some of modification in extrapolation expression of NATO standard AOP-48 Ed. 2.
Jelisavac Ljiljana, Stojiljković Slaviša, Brzić Saša, Nešić Jovica, Fidanovski Bojana, Tanaskovski Bojan   +5 more
doaj  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source