In AKI, initial kidney injury upregulates the expression of Cav‐1, which subsequently binds to and stabilizes SERCA2 via its scaffolding domain and through deubiquitination, thereby regulating Ca2+ homeostasis and ER stress. Conversely, Cav‐1 deficiency accelerates SERCA2 degradation, triggering Ca2+ overload and ER stress, and ultimately exacerbating ...
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A neural controller for a natural circulation loop
2001 European Control Conference (ECC), 2001This paper presents a neural network based approach to the identification and control of an experimental natural circulation loop. The aim of the model is to predict the dynamical evolution of the oscillations, characterizing the system dynamics in some operating conditions and that can cause dangerous flow reversal.
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