Results 21 to 30 of about 15,624 (253)

A Decoy‐Receptor‐Armed Biomimetic Nanotherapeutic With Inherent Tropism for Conserved Pathogenic Macrophages for Treating Osteoarthritis and Intervertebral Disc Degeneration

Advanced Science, EarlyView.
A biomimetic doppelgänger nanosystem neutralizes extracellular inflammatory cytokines and silences intracellular pyroptosis, reprogramming pathogenic macrophages to attenuate both joint and spine degeneration. ABSTRACT Osteoarthritis (OA) and intervertebral disc degeneration (IVDD) are debilitating musculoskeletal disorders driven by shared ...
Fudong Li, Bin Zhang, Zhiqiu Zhang, Bing Zheng, Linhui Han, Chen Yan, Jialin Li, Kaiqiang Sun, Tianyi Zhao, Jiangang Shi   +9 more
wiley   +1 more source

Trehalose accumulation contributes to enhanced cold stress tolerance in Telenomus remus, a dominant egg parasitoid of Spodoptera frugiperda

BMC Genomics
Telenomus remus is a highly efficient biological control agent against Spodoptera frugiperda, owing to its capacity to successfully locate and parasitize inner layer eggs of egg masses.
Wanbin Chen, Huan Liu, Yuyan Li, Mengqing Wang, Jianjun Mao, Zhijie Guo, Lisheng Zhang   +6 more
doaj   +1 more source

Dual‐Targeting Biomimetic Nanozymes Loaded Microneedle Patch Promotes Scarless Wound Healing Through Anti‐Inflammatory and Anti‐Fibrotic Effects

Advanced Science, EarlyView.
This study developed a dual‐targeting biomimetic nanozyme hybrid system (Cu‐CeO2@ABs‐FTP) and integrated it with HAMA hydrogel to fabricate a microneedle patch (CAF@MN). The patch promotes fibroblast‐mediated wound repair, targets macrophages to induce M2 polarization, and targets myofibroblasts to exert anti‐fibrotic effects, thereby enabling rapid ...
Hongyi Zhang, Jinwei Li, Shan Hua, Shengming Wu, Chenlong He, Yuan Zhu, Ming Yin, Han Zhou, Huawei Liu, Chika Hasegawa, Jun Lyu, Keyue Xiao, Hua Jiang, Yilong Wang, Yuxin Qian   +14 more
wiley   +1 more source

Herbivory‐Induced Stomatal Opening Triggers the Dispersal of an Invasive Insect Herbivore

Advanced Science, EarlyView.
The invasive leafminer Phthorimaea absoluta uniquely manipulates plant defenses by inducing stomatal opening in tomato. This response, mediated by the stomatal regulator IQM1, enhances the release of the repellent volatile benzaldehyde. This volatile triggers the dispersal of adult moths, facilitates colonization of new hosts, and leads to rapid ...
Limin Chen, Xiaowei Li, Yaru Wang, Farman Ullah, Shuxing Zhou, Lemeng Dong, Weizhong He, Harro J. Bouwmeester, Youming Hou, Ian T. Baldwin, Yaobin Lu   +10 more
wiley   +1 more source

Biological Control Potential of the Reduviid Predator Rhynocoris fuscipes (Fabricius) in Managing Noctuid Pests: Insights Into Predation and Prey Preference

Insects
Understanding predator–prey and predator–predator interactions is essential for evaluating the effectiveness of biocontrol agents and developing efficient pest management strategies.
Chuanzhen Xue, Jiaying Mao, Bowen Xu, Lei Zhou, Haihang Zhou, Jianjun Mao, Zhongjian Shen, Lisheng Zhang, Mengqing Wang, Yuyan Li   +9 more
doaj   +1 more source

Stability of Cacopsylla pyricola (Hemiptera: Psyllidae) Populations in Pacific Northwest Pear Orchards Managed with Long-Term Mating Disruption for Cydia pomonella (Lepidoptera: Tortricidae)

Insects, 2017
This study focused on conservation biological control of pear psylla, Cacopsylla pyricola, in the Pacific Northwest, USA. We hypothesized that insecticides applied against the primary insect pest, codling moth Cydia pomonella, negatively impact natural ...
Kaushalya G. Amarasekare, Peter W. Shearer   +1 more
doaj   +1 more source

Lack of phenotypic and evolutionary cross-resistance against parasitoids and pathogens in Drosophila melanogaster. [PDF]

PLoS ONE, 2012
When organisms are attacked by multiple natural enemies, the evolution of a resistance mechanism to one natural enemy will be influenced by the degree of cross-resistance to another natural enemy.
Alex R Kraaijeveld, Sophie J Layen, Peter H Futerman, H Charles J Godfray   +3 more
doaj   +1 more source

Autophagy Orchestrates Anti‐Tumor Immunity to Enhance Chemosensitivity via the FBXW2/C/EBPβ/TIMP‐2 Axis in Colorectal Cancer

Advanced Science, EarlyView.
Chemotherapy leverages tumor‐cell autophagy to reshape the colorectal cancer immune microenvironment. Autophagy degrades FBXW2 to promote C/EBPβ‐mediated TIMP‐2 transcription and MMP‐9 suppression, driving intra‐tumoral CD8+ T‐cell infiltration. Targeting MMP‐2/9 or restoring TIMP‐2 overcomes chemo‐resistance in autophagy‐deficient tumors. ABSTRACT The
Bing Cheng, Chaoying Wei, Zhitong Niu, Jinxin Chen, Guojie Long, Yingzhen Weng, Qiufeng Liu, Yue Jiang, Panpan Wang, Ronghua Zhang, Qiang Yu, Xiaojian Wu, Wenyu Wang   +12 more
wiley   +1 more source

Comparative transcriptome analysis provides a glance into the regulation of the Krüppel homolog 1 on the reproduction and diapause of the predatory ladybeetle, Coccinella septempunctata

BMC Genomics
As a typical natural predator of agricultural pests, the lady beetle, Coccinella septempunctata, has been commercially mass-reared and widely employed in in pest management.
Junjie Chen, Xiaoxiao Liu, Shunda Han, Maosen Zhang, Zhaohan Liu, Yuyan Li, Lisheng Zhang   +6 more
doaj   +1 more source

Acute Toxicity of Dinotefuran to Picromerus lewisi Scott (Hemiptera: Pentatomidae) and Its Impact on Offspring Growth and Predation Ability in Integrated Pest Management

Insects
In integrated pest management (IPM), achieving a balance between biological and chemical control strategies is essential for effective pest control. Therefore, it is crucial to assess the impact of chemical pesticides on natural enemies.
Yutong Ji, Mengqing Wang, Chuanzhen Xue, Jianjun Mao, Yuyan Li, Lisheng Zhang   +5 more
doaj   +1 more source