Results 51 to 60 of about 5,709,277 (284)
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
State responsibility for environmental damage [PDF]
مجلة الاجتهاد للدراسات القانونية والاقتصادية, 2020 In this speech, we take the international responsibility for the violation of the natural environment because the subject of environmental pollution is one of the fertile subjects, because societies do not have environmental awareness and its importance,
Maddah Abdellatif, Mansouri Al Mabrouk
doaj
Rebecca Rowe: Professor of Natural Resources and the Environment [PDF]
, 2019 Rebecca Rowe is an associate professor and program coordinator for wildlife and conservation biology in the Department of Natural Resources and the Environment at the University of New Hampshire. Below is a correspondence with Dr.
Trainer, Erin
core +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Revue Archéologique du Centre de la France, 2009 The rescue excavation of the Marais du Colombier site, Varennes-sur-Seine (Seine-et-Marne) enabled us to study a rural establishment dating back to the first half of the 3rd century BC set in a damp low-lying area of the plain situated in the lower ...
Jean-Marc Séguier +5 more
doaj
Quantitative Methodology for Measuring Natural Character in New Zealand's Coastal Environments [PDF]
, 2011 Anecdotal evidence points to an overall loss of coastal natural character in New Zealand since preserving the natural character of the coastal environment first became a statutory policy-goal in 1973.
Froude, Victoria Ann
core +1 more source
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source