Results 71 to 80 of about 1,376,167 (262)
Emotional regulation and self-perceived quality of life in high-performance mountain sports athletes
Frontiers in PsychologyEmotional regulation is an indispensable capacity for human beings, so that alterations in it can lead to the appearance of psychological, social and/or cognitive disorders. Therefore, possessing adequate emotional strategies is intimately related to the
Pablo Rojo-Ramos +4 more
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Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
Detection of Citrus Huanglongbing in Natural Field Conditions Using an Enhanced YOLO11 Framework
MathematicsCitrus Huanglongbing (HLB) is one of the most devastating diseases in the global citrus industry, but its early detection under complex field conditions remains a major challenge. Existing methods often suffer from insufficient dataset diversity and poor
Liang Cao +4 more
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PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
The interaction of the architecture of Asbad of Varmal settlement with the characteristics of the natural environment in terms of orientation with the 120-day winds of Sistan [PDF]
مسکن و محیط روستاAsbads are a sign of creativity, initiative and innovation of Iranians in the hot and dry climate and windy areas of eastern Iran. The 120 day winds have been the main factor and motivation for the invention of Asbads in Sistan region.
Naghmeh Behboodi, Akbar Kiani
doaj
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Risk assessment of lead and cadmium on Juveniles of Cyprinus carpio in laboratory scale
Vietnam Journal of Science, Technology and Engineering, 2018 This paper assesses the risk of lead and cadmium heavy metals on Cyprinus carpio in laboratory conditions. The research determined the 96 hours LC50 value of lead nitrate and cadmium nitrate in the fish Cyprinus carpio.
Thi Yen Ta +5 more
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FEBS Open Bio, EarlyView.Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin +3 more
wiley +1 more source