Results 61 to 70 of about 11,921,961 (287)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Colors Inspired by Nature Analyzed in Two Residential Buildings Designed by Victor Horta

open access: yesArts, 2021
The aim of the article is to present the results of research on colors carried out in two residential buildings in Brussels, designed by Victor Horta: The Tassel House (1893–1894) and The Horta House (1898–1901), representing the Art Nouveau style for ...
Barbara Widera
doaj   +1 more source

Will the Sustainable Development Goals address the links between poverty and the natural environment?

open access: yesCurrent Opinion in Environmental Sustainability, 2018
The relationships between the natural environment and poverty have been a central theme in the sustainability and development literatures. However, they have been less influential in mainstream international development and conservation policies, which ...
J. Schleicher, M. Schaafsma, B. Vira
semanticscholar   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Carbonate Precipitation through Microbial Activities in Natural Environment, and Their Potential in Biotechnology: A Review

open access: yesFrontiers in Bioengineering and Biotechnology, 2016
Calcium carbonate represents a large portion of carbon reservoir and is used commercially for a variety of applications. Microbial carbonate precipitation, a by-product of microbial activities, plays an important metal coprecipitation and cementation ...
Tingting Zhu, M. Dittrich
semanticscholar   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Advancing Environmental Epidemiology to Assess the Beneficial Influence of the Natural Environment on Human Health and Well-Being.

open access: yesEnvironmental Science and Technology, 2018
Environmental health research can be oriented across a continuum of effects ranging from adverse to cobenefits to salutogenic. We argue that the salutogenic end of the continuum is insufficiently represented in research and as a basis for environmental ...
Raquel A. Silva, K. Rogers, T. Buckley
semanticscholar   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Climate Change and Water-Related Infectious Diseases

open access: yesAtmosphere, 2018
Background: Water-related, including waterborne, diseases remain important sources of morbidity and mortality worldwide, but particularly in developing countries.
Gordon Nichols   +2 more
doaj   +1 more source

Continuous moulting by Antarctic krill drives major pulses of carbon export in the north Scotia Sea, Southern Ocean

open access: yesNature Communications, 2020
Antarctic krill are known to be important to the carbon cycle, but the exact contribution is not known. Here the authors show that krill moulting is a major vector of carbon export in the Southern Ocean, together with krill faecal pellets accounting for ...
C. Manno   +5 more
doaj   +1 more source

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