Results 41 to 50 of about 572,242 (262)

Family-centered approach in Early Childhood Intervention of a vulnerable population from an Ecuadorian rural context

Frontiers in Psychology, 2023
IntroductionStudies about the implementation of the Family Centered Practices approach in Early Childhood Intervention refer as outcomes that have an impact on the Quality of Family Life, on children’s development, and also on family empowerment.
Marcela Frugone-Jaramillo, Marta Gràcia
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

STAND FOR TEMPERATURE SURFACE EVALUATION OF FRAGMENTS OF NATURAL ENVIRONMENTS AND ITS IMITATORS

Приборы и методы измерений, 2016
Research in the field of development of natural environments imitators that used for thermal cloaking of military machinery always connected with high material costs due to big sizes of cloaking objects.
V. V. Lobunov, A. I. Kuharenko, T. V. Borbotko, L. M. Lynkov   +3 more
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Evaluation of toxicity and ecological risk assessment of heavy metals in surface sediments of Sezar River, Lorestan Province

سلامت و محیط, 2019
Background and Objective: Considering the toxicity, health and ecological hazards of heavy metals in the environment and the impact on organisms, it looks essential to measure and evaluate their concentrations at the various levels in indigineous ...
S Mortazavi, M Hatami-Manesh, F Joudaki
doaj  

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Effect of Nature-based physical activity on post-traumatic growth among Healthcare providers with post-traumatic Stress: Protocol for a randomized controlled trial.

International Journal of Endorsing Health Science Research, 2020
Background:In the aftermath of trauma, post-traumatic growth is demarcated as a positive change and traumatic stress as a negative change, which further leads to PTSD.
Shamoon Noushad, Basit Ansari, Sadaf Ahmed, Yusra Saleem   +3 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source