Results 51 to 60 of about 175,990 (247)
Peptomer Linkers Enable Kinetic Control over Co‐Delivery of Multiple Chemotherapeutics
Advanced Healthcare Materials, EarlyView.A key challenge in combinatorial chemotherapeutic drug delivery is independent control over release kinetics, especially with drugs of similar size and structure. Here, peptoid substitutions to proteolytically degradable peptides enabled the design of fast and slow‐releasing drug linkers.
Carolyn M. Watkins +3 more
wiley +1 more source
Itô-vector projection filter for exponential families
Results in Applied MathematicsIn this paper, we study the application of Itô-vector projection [1] to the optimal filtering problem. The algorithm projects one SDE to another, possibly lower dimensional, SDE by minimizing an Itô–Taylor expansion of the local projection error’s L2 ...
Muhammad Fuady Emzir
doaj +1 more source
Constant Step Size Stochastic Gradient Descent for Probabilistic Modeling [PDF]
, 2018 Stochastic gradient methods enable learning probabilistic models from large amounts of data. While large step-sizes (learning rates) have shown to be best for least-squares (e.g., Gaussian noise) once combined with parameter averaging, these are not ...
Babichev, Dmitry, Bach, Francis
core +2 more sources
The Atiyah--Hitchin bracket and the open Toda lattice
, 2002 The dynamics of finite nonperiodic Toda lattice is an isospectral deformation of the finite three--diagonal Jacobi matrix. It is known since the work of Stieltjes that such matrices are in one--to--one correspondence with their Weyl functions.
Beals +15 more
core +1 more source
Advanced Materials, EarlyView.A 3D‐printed BSA–PEGDA bilayer actuator performs biochemical logic, bending autonomously in acid and releasing its drug payload only when both acid and pepsin are present. This dual‐stage, enzyme‐gated mechanism enables autonomous catch‐and‐release motion and controlled gastric drug delivery, representing a programmable soft material powered by ...
Yuchen Liu +3 more
wiley +1 more source
Natural Gradient Flow in the Mixture Geometry of a Discrete Exponential Family [PDF]
Entropy, 2015 In this paper, we study Amari’s natural gradient flows of real functions defined on the densities belonging to an exponential family on a finite sample space. Our main example is the minimization of the expected value of a real function defined on the sample space.
Malagò, Luigi, Pistone, Giovanni
openaire +4 more sources
Ramsey Theory Problems over the Integers: Avoiding Generalized Progressions [PDF]
, 2015 Two well studied Ramsey-theoretic problems consider subsets of the natural numbers which either contain no three elements in arithmetic progression, or in geometric progression.
Best, Andrew +6 more
core
Advanced Materials, EarlyView.Magnetic tunnel junctions (MTJs) using MgO tunnel barriers face challenges of high resistance‐area product and low tunnel magnetoresistance (TMR). To discover alternative materials, Literature Enhanced Ab initio Discovery (LEAD) is developed. The LEAD‐predicted materials are theoretically evaluated, showing that MTJs with dusting of ScN or TiN on ...
Sabiq Islam +6 more
wiley +1 more source
Reproducibility and Natural Exponential Families with Power Variance Functions
The Annals of Statistics, 1986 Let \(X_ 1\),..., \(X_ n\) be independent identically distributed random variables whose common distribution belongs to a family \({\mathcal F}=\{F_{\theta}\in \Theta \subset {\mathbb{R}}\}\) indexed by a parameter \(\theta\). We say that \({\mathcal F}\) is reproducible if there exists a sequence \(\{\) \(\alpha\) (n)\(\}\) such that \[ {\mathcal L ...
Bar-Lev, Shaul K., Enis, Peter
openaire +2 more sources
Exponential families, Kahler geometry and quantum mechanics
, 2012 Exponential families are a particular class of statistical manifolds which are particularly important in statistical inference, and which appear very frequently in statistics.
Amari +33 more
core +1 more source