Results 221 to 230 of about 396,333 (302)

Clinical Evaluation of Drug–Drug Interactions Between Bictegravir and Strong Inhibitors/Inducers of the CYP3A4, UGT1A1, or P‐gp Pathways

open access: yesThe Journal of Clinical Pharmacology, EarlyView.
Abstract In addition to antiretroviral therapy (ART), people with HIV often take medications to treat comorbidities. It is therefore important to assess these medications for potential drug‐drug interactions, which may affect the safety and efficacy of ART. Three phase I studies were conducted in adult participants without HIV. The pharmacokinetics (PK)
Priyanka Arora   +4 more
wiley   +1 more source

Noncanonical Nucleotides in the Genome Around the Maternal‐Zygotic Transition

open access: yesJournal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
In this paper, Kazzazi et al. provide a comprehensive review of the dynamics of nonconventional nucleotides in the genome during early developmental stages, hypothesizing a potential role for these nucleotides in the activation of the zygotic genome. ABSTRACT From the very moment of fertilization and throughout development, the cells of animal embryos ...
Latifa Kazzazy   +7 more
wiley   +1 more source

Para-Markov chains and related non-local equations. [PDF]

open access: yesFract Calc Appl Anal
Facciaroni L   +3 more
europepmc   +1 more source

A Nordhaus–Gaddum Problem for the Spectral Gap of a Graph

open access: yesJournal of Graph Theory, EarlyView.
ABSTRACT Let G $G$ be a graph on n $n$ vertices, with complement G¯ $\bar{G}$. The spectral gap of the transition probability matrix of a random walk on G $G$ is used to estimate how fast the random walk becomes stationary. We prove that the larger spectral gap of G $G$ and G¯ $\bar{G}$ is Ω(1∕n) ${\rm{\Omega }}(1\unicode{x02215}n)$.
Sooyeong Kim, Neal Madras
wiley   +1 more source

Nudging Tactics for Enhanced Compliance With Condition‐Based Maintenance Guidelines

open access: yesJournal of Operations Management, EarlyView.
ABSTRACT Condition‐based preventive maintenance (CB‐PM), dependent on robust and precise indicators of equipment quality, stands to gain advantages from the integration of sensor technologies. Yet, the effectiveness of such systems relies on an important factor: people.
Mateus do Rego Ferreira Lima   +3 more
wiley   +1 more source

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