Results 101 to 110 of about 3,804,515 (284)
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Illinois Natural History Survey Annual Report FY2005
Open Restriction set for Item 105622 on 2018-04-12T19:26:52Z with date null by joellat2@illinois.edu.Submitted by Joella Travis (joellat2@illinois.edu) on 2018-04-12T19:36:10Z No.
Illinois Natural History Survey
core +1 more source
this document. The text in those locations is normative, rather than what is given here; the purpose of this appendix is to provide a summary of those extensions.
Protocol Extensions
core
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source
Monogenic Functions in Conformal Geometry
Monogenic functions are basic to Clifford analysis. On Euclidean space they are defined as smooth functions with values in the corresponding Clifford algebra satisfying a certain system of first order differential equations, usually referred to as the ...
Michael Eastwood, John Ryan
doaj
λ-Analogues of Stirling polynomials of the first kind and their applications
Recently, λ-analogues of Stirling numbers of the first kind were studied. In this paper, we introduce, as natural extensions of these numbers, λ-Stirling polynomials of the first kind and r-truncated λ-Stirling polynomials of the first kind.
Taekyun Kim +3 more
doaj +1 more source
A Natural Extension of the BK Inequality
We extend the seminal van den Berg-Kesten Inequality on disjoint occurrence of two events to a setting with arbitrarily many events, where the quantity of interest is the maximum number that occur disjointly. This provides a handy tool for bounding upper tail probabilities for event counts in a product probability space.
Baron, Jacob D., Kahn, Jeff
openaire +2 more sources
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source

