Results 41 to 50 of about 47,533 (149)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

WSPÓŁCZESNE OCIEPLENIE W REJONIE MORZA BAŁTYCKIEGO A ZMIANA REŻIMU LODOWEGO TEGO MORZA [PDF]

Przegląd Geofizyczny
This paper discusses climate change in the Baltic region and changes in heat resources in its waters that occurred during the last warming period (after 1988). Attention is drawn to the systematic increase in SST, indicating an increase in heat resources
Andrzej A. Marsz, Anna Styszyńska
doaj   +1 more source

Cognitive Functions, Neurotransmitter Alterations, and Hippocampal Microstructural Changes in Mice Caused by Feeding on Western Diet

Cells, 2023
Metabolic Dysfunction Associated Steatotic Liver Disease (MASLD) is the most common chronic liver disease in Western countries. It is becoming increasingly evident that peripheral organ-centered inflammatory diseases, including liver diseases, are linked
Raly James Perez Custodio, Zaynab Hobloss, Maiju Myllys, Reham Hassan, Daniela González, Jörg Reinders, Julia Bornhorst, Ann-Kathrin Weishaupt, Abdel-latif Seddek, Tahany Abbas, Adrian Friebel, Stefan Hoehme, Stephan Getzmann, Jan G. Hengstler, Christoph van Thriel, Ahmed Ghallab   +15 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Land use change projection and driving factors exploration in Hainan Island based on the PLUS model

Frontiers in Marine Science
IntroductionLand resources play a vital role in national economic and social development. Hainan Province faces the challenge of balancing land use with conservation while striving to develop a high-quality free trade port.
Jiahui Liu, Yaoqi Hou, Fangyi Li, Binbin Zheng, Zeheng Chen, Fa Zheng, Xiaohai Zhang, Rui Yu   +7 more
doaj   +1 more source

Stališča o vplivih ključnih naravnih dejavnikov pri vrednotenju nepremičnin s poudarkom na poplavnosti ; Positions of the impact of natural factors on real estate appraisal with an emphasis on flooding [PDF]

Geodetski Vestnik, 2012
V prispevku razpravljamo o vlogi naravnih dejavnikov, kot so plazovitost, poplavnost, osončenost, razglednost, količina meglenih in jasnih dni, vetrovnost, kakovost zraka, hrup ter pogostost toče in žleda, pri vrednotenju nepremičnin.
Nina Langerholc, Bojan Grum
doaj  

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source