Results 211 to 220 of about 62,872 (295)

A diagnostic model based on pulmonary microbiota and host gene expression to distinguish colonization from pneumonia. [PDF]

Sci Rep
Fu Z, Sun Y, Yao H, Liu Q, Zhang Q, Hu J, Zhou Y, Jiang N, Ai J, Jin J, Zhang W.   +10 more
europepmc   +1 more source

Activation of ERBB4 Pathway Inhibits Pathological Transdifferentiation of Lung Epithelial Progenitors into CD66c+ Basal Cells in Severe Lung Injury

Advanced Science, EarlyView.
In fibrotic distal lung regions, CD66c+ basal cells emerge as a pathological state. Using human distal lung organoids, this study identifies CD66c+ basal cells as a pro‐fibrotic state arising through transdifferentiation from secretory, AT2, and basal cells.
Kaijun Lin, Xinran Deng, Haonan Wang, Yamei Jiang, Jian Sun, Hailin Ding, Ming Ye, Xiaoting Wang, Yu Wang, Li Yuan, Zhenju Song, Xinhua Lin, Shenfei Sun, Ning Jiang   +13 more
wiley   +1 more source

Persistent trade-offs balance competition and colonization across centuries. [PDF]

Proc Natl Acad Sci U S A
Backman T, Cui J, Caullireau E, Bleak E, Bezrukov I, Girardi P, Hawks A, Lasky JR, Latorre SM, Erberich JM, Lopez L, Neumann M, Perkins AM, Symeonidi E, Azadi P, Horvath MP, Muszyński A, Lang PLM, Karasov TL, Burbano HA.   +19 more
europepmc   +1 more source

3D Chromatin Architecture Provides Insights Into Leaf Trait Variation Among Pear Species

Advanced Science, EarlyView.
ABSTRACT Three‐dimensional (3D) chromatin architecture plays a fundamental role in eukaryotic gene regulations, its functional significance in perennial fruit trees remains poorly characterized despite extensive applications in crop genomics. Here, we developed high‐resolution (∼5 kb) Hi‐C maps of Pyrus and compared 3D genomic architecture of three ...
Yueyuan Liu, Chenhui Han, Cheng Xue, Manyi Sun, Bobo Song, Yongsong Xue, Guangyan Yang, Shaozhuo Xu, Wei Wei, Jiaming Li, Runze Wang, Jun Wu   +11 more
wiley   +1 more source

Bronchial Atresia Presenting With Recurrent Pneumonia in an Adult With Asthma: The Importance of Post-infectious Radiological Reassessment. [PDF]

Cureus
Carneiro G, Aranha R, Macedo B.
europepmc   +1 more source

Sex‐Specific Regulation of Glycemic Homeostasis by Theabrownin from Pu‐erh Tea

Advanced Science, EarlyView.
Pu‐erh tea's key component, theabrownin (TB), lowers blood glucose in a sex‐specific manner. In females, estrogen boosts intestinal MUC2 production, which dramatically enhances TB's ability to inhibit the carbohydrate‐digesting enzyme α‐glucosidase.
Yang Li, Junliang Kuang, Dan Zheng, Jieyi Wang, Kun Ge, Chun Qu, Xiaojiao Zheng, Zhenxing Ren, Fengjie Huang, Mingliang Zhao, Yimin Sun, Huiheng Zhang, Keke Ding, Xixi Xia, Yajun Tang, Lu Liu, Jian Zhou, Fei Gao, Xiaohui Ma, Yongquan Xu, Guoxiang Xie, Aihua Zhao, Wei Jia   +22 more
wiley   +1 more source

Congenital hypospadias complicated with pelvic cystic lesions and accessory urethra:A case report. [PDF]

Urol Case Rep
Madanyeti A, Zheng Z, Tang F, Peng J.
europepmc   +1 more source

PRC2.1 Coordinates Peri‐Nucleolar H3K27me3‐Enriched Heterochromatin Organization and NPM1 Pentamerization to Maintain Nucleolar Integrity

Advanced Science, EarlyView.
PRC2.1(PCL2)‐coordinated H3K27me3‐enriched PNH establishes a spatial scaffold crucial for nucleolar integrity. As a crucial coordinator, PCL2 links PRC2.1 to chromatin organization and NPM1 assembly. This network‐based model reveals how chromatin modifications and nucleolar components cooperatively maintain nucleolar architecture, revealing novel ...
Lina Zhu, Wenqin Wang, Shuyun Chen, Gangyi Zhu, Zhen Wu, Yue Gu, Jingwen Xiong, Xu Zhang, Heng Liu, Kyoichi Isono, Youming Zhang, Jingjing Cao, Xiangzhi Li   +12 more
wiley   +1 more source

Hybrid Congenital Pulmonary Malformation Revealed by Chronic Hemoptysis in a Six-Year-Old Girl: A Case Report. [PDF]

Cureus
Abdourabbih Y, Amelouagh A, Ouazzani H, Chaouche I, Akammar A, El Bouardi N, Alami B, Lamrani Y, Maaroufi M, Boubbou M.   +9 more
europepmc   +1 more source