Results 261 to 270 of about 131,329 (306)

Decoding Triphenotypic Neutrophils in Cervical Cancer Evolution and Targeting SPP1+/GBP1+/ELOVL5+ Tumor‐Associated Neutrophils to Sensitize Immunotherapy

open access: yesAdvanced Science, EarlyView.
The functional schematic diagram of tumor associated neutrophils. Abstract Enhancing cervical cancer (CC) immunotherapy requires deciphering the heterogeneous tumor immune microenvironment (TIME), particularly neutrophil phenotypic dynamics. Here, 1) we collected 543 CC cases to find that patients with elevated neutrophil levels have a higher incidence
Xingyu Chang   +7 more
wiley   +1 more source

De Novo Multi‐Mechanism Antimicrobial Peptide Design via Multimodal Deep Learning

open access: yesAdvanced Science, EarlyView.
Current AI‐driven peptide discovery often overlooks complex structural data. This study presents M3‐CAD, a generative pipeline that leverages 3D voxel coloring and a massive database of over 12 000 peptides to capture nuanced physicochemical contexts.
Xiaojuan Li   +23 more
wiley   +1 more source

Amyloid-related imaging abnormalities (ARIA) in Alzheimer's immunotherapy: a framework and challenges for global surveillance strategies. [PDF]

open access: yesJ Neurol Neurosurg Psychiatry
Hu N   +11 more
europepmc   +1 more source

A Tac1‐Expressing Brainstem Pathway Underlies the Pathogenesis of Trigeminal Neuralgia

open access: yesAdvanced Science, EarlyView.
A critical TG‐Sp5CTac1‐PBNTac1 pathway drives trigeminal neuropathic pain (TNP). Tac1‐expressing parabrachial nucleus (PBNTac1) neurons exhibit heightened responses to innocuous stimuli in TNP, and chemogenetic inhibition of these neurons effectively prevents TNP development.
Liting Sun   +11 more
wiley   +1 more source

A Woman With Fever, Odynophagia, and Progressive Dyspnea. [PDF]

open access: yesJ Am Coll Emerg Physicians Open
Li X, Fu R, Zhou X, Gu Q, Yang W.
europepmc   +1 more source

Global evolutionary landscape of H11 avian influenza and initial isolates identified in Xinjiang, China. [PDF]

open access: yesEmerg Microbes Infect
Li Y   +11 more
europepmc   +1 more source

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