Compound Heterozygote Friedreich Ataxia Patients With Covert Proximal FXN Gene Deletions
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT We present Friedreich ataxia patients with frataxin gene deletions. Data and records were collected at the Children's Hospital of Philadelphia from patients enrolled in the FACOMS natural history study. Patients with proximal deletions initially diagnosed with only one GAA expanded allele had more severe disease than their homozygous expansion
Michael P. Lazaropoulos +5 more
wiley +1 more source
The Influence of Second-Order Effects on the Critical Load Multiplier and Natural Frequencies of a Low-Rise Steel Dome. [PDF]
Materials (Basel)Zabojszcza P, Obara P, Radoń U.
europepmc +1 more source
Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin +11 more
wiley +1 more source
Natural Frequencies of Waves In Helical Springs
International Journal on Orange TechnologiesThis paper explores the natural frequencies of vibrations in helical springs through both theoretical analysis and computational methods. Helical springs are crucial elastic components widely used in various mechanical systems, serving primarily to absorb loads and mitigate vibrations.
openaire +2 more sources
Analytical investigation of natural frequencies and mode shapes of a multi-span beam with a disc and spring supports. [PDF]
Sci RepSharma V, Agnihotri SK, Rawat M.
europepmc +1 more source
, 2015 Chancel Frequencies at 20-21 Arts Centre featured three works especially selected to respond to the former church building as a contemplative space, portraying images of sound, which are otherworldly, and designed to encourage contemplation.
Locke, Caroline
core
MOGAD Is the Most Common Cause of Isolated Optic Neuritis in Children
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives The study aimed to characterize the clinical features, etiologies, and outcomes of isolated, first‐time pediatric ON in the post‐MOG‐IgG era. Methods This was a single‐center retrospective cohort study at Texas Children's Hospital of patients diagnosed with first‐time ON between 2018–2024, with follow‐up data collected through 2025.
Chaitanya Aduru +13 more
wiley +1 more source
Wonders of Harbor and Grey Seal Whiskers: Morphology, Natural Frequencies, and 3D Modeling. [PDF]
Adv Sci (Weinh)Zheng X +4 more
europepmc +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To characterize the demographic, clinical, and laboratory features of the Chinese patients of genetic Creutzfeldt‐Jakob disease with T188K variant (T188K‐gCJD), the most common subtype of genetic prion diseases (gPrDs) in China. Methods In this nationwide retrospective study, data from 98 genetically confirmed T188K‐gCJD patients ...
Chun‐Jie Li +11 more
wiley +1 more source
Risk expression using likelihood ratios and natural frequencies in Bayesian inference tasks-a preregistered randomized-controlled crossover trial. [PDF]
BMC Med EducSchulz P, Wegwarth O, Giese H.
europepmc +1 more source