Results 41 to 50 of about 379,760 (213)
Operational Modal Analysis of the Cablestayed Footbridge
Civil and Environmental Engineering, 2017 Modern architecture leads to design subtle bridge structures that are more sensitive to increased dynamic loading than the massive ones. This phenomenon can be especially observed on lightweight steel structures such as suspended footbridges. As a result,
Kortiš Ján +4 more
doaj +1 more source
Multiple crack identification in stepped beam by measurements of natural frequencies
Vietnam Journal of Mechanics, 2014 A new approach is proposed for calculating natural frequencies and crack detection in a stepped cantilever beam with arbitrary number of cracks. This is based an explicit expression of the natural frequencies in term of crack parameter derived in the ...
Nguyen Tien Khiem +2 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Structure and Properties of Doped with Nitrogen and Vanadium High-Carbon Steels
Механика машин, механизмов и материалов, 2015 Free planar and bending interfacial and boundary vibrations of semi-infinite composed plates and plate-strips are studied. Using the system of equations of the related classical theory of orthotropic plates, dispersion equations and asymptotic formulas ...
Petr A. Vityaz +5 more
doaj
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
FEBS Letters, EarlyView.Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Journal of Manufacturing and Materials Processing, 2020 During the milling of thin-walled workpieces, the natural frequencies might change radically due to the material removal. To avoid resonant spindle speeds and chatter vibration, a precise knowledge of the instantaneous modal parameters is necessary. Many
Daniel Bachrathy +5 more
doaj +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Natural vibration frequencies of tapered beams Engineering
Engineering Transactions, 2014 In this paper the free vibrations frequencies of tapered Euler-Bernoulli beams are calculated, in the presence of an arbitrary number of rotationally and/or axially, elastically flexible constraints.
M. A. DE ROSA, M. LIPPIELLO
doaj