Results 121 to 130 of about 1,186,086 (313)
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Empirical model of natural frequency for single span integral bridge [PDF]
Natural frequency has been used as a reliable indicator for damage and condition assessment in civil engineering application, where the in situ natural frequency is compared to the theoretical natural frequency to determine the condition of a structure ...
Ibrahim, Muhammad Khairil
core
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Methods of frequency tuning vibration based micro-generator
A vibration based micro-generator is an energy harvesting device that couples a certain transduction mechanism to the ambient vibration and converts mechanical energy to electrical energy.
Zhu, Dibin
core
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
Experimental Study of Bridge Expansion Joint Damage Based on Natural Frequency. [PDF]
Li J +6 more
europepmc +1 more source
Statistics of gradient directions in natural images.
Interest in finding statistical regularities in natural images has been growing since the advent of information theory and the advancement of the efficient coding hypothesis that the human visual system is optimised to encode natural visual stimuli.
Nasrallah, A.J. +1 more
core
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef +2 more
wiley +1 more source
Correction to 'Natural Frequency Method: estimating the preferred walking speed of Tyrannosaurus rex based on tail natural frequency'. [PDF]
van Bijlert PA +2 more
europepmc +1 more source

