Results 51 to 60 of about 1,091,840 (264)

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Effects caused by degeneration of natural frequency for pneumatic isolated table with two degrees-of-freedom

open access: yesNihon Kikai Gakkai ronbunshu, 2018
In this paper, it is confirmed that natural frequency of isolated table is operated and that degeneration, which means that some natural frequencies have the same value, has a bad influence. Pneumatic anti vibration apparatuses (AVAs) support that loaded
Yui AOKI, Shinji WAKUI
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Numerical Study of Frequency and Deflection Responses of Natural Fiber (Luffa) Reinforced Polymer Composite and Experimental Validation

open access: yesJournal of Natural Fibers, 2020
The natural fiber (Luffa cylindrica fiber) reinforced epoxy composite has been fabricated and their structural responses (frequency and deflection) have been computed experimentally and numerically first time using the corresponding experimental elastic ...
Hitesh B. Bisen   +5 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

FBG-Based Accelerometer for Buried Pipeline Natural Frequency Monitoring and Corrosion Detection

open access: yesBuildings
Pipelines are structures with great relevance in different industrial sectors and are essential for the proper functioning of the logistics that support today’s society.
Luís Pereira   +7 more
doaj   +1 more source

DAMAGE DETECTION IN COMPOSITE CYLINDRICAL PANEL BASED ON FORCED VIBRATION ANALYSIS [PDF]

open access: yesScientific Journal of Silesian University of Technology. Series Transport, 2014
The current work is devoted to the damage detecting inside the composite cylindrical panels. The applied method is based on the analysis of the natural vibration and corresponding mode shapes.
Piotr PAJĄK, Marek BARSKI
doaj  

What are natural frequencies? [PDF]

open access: yesBMJ, 2011
Doctors need to find better ways to communicate risk to patients A 2011 Cochrane Review concluded that health professionals and consumers “understood natural frequencies better than probabilities.”1 A 2011 Annals of Internal Medicine article reported the opposite, that “natural frequencies are not the best format for communicating the absolute ...
openaire   +2 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

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