Results 71 to 80 of about 1,186,086 (313)

The pyruvate generator is a common phenomenon in mitochondria from different rat and mouse brain regions

open access: yesFEBS Letters, EarlyView.
The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber   +7 more
wiley   +1 more source

Dynamic Response of a 15 MW Jacket-Supported Offshore Wind Turbine Excited by Different Loadings

open access: yesEnergies
This study investigates the dynamic behavior of a jacket-supported offshore wind turbine (JOWT) by developing its substructure and controller tailored for the IEA 15 MW reference wind turbine.
Renqiang Xi   +3 more
doaj   +1 more source

Proposal of self-standing support method for vibration reduction of refrigerator compressors

open access: yesNihon Kikai Gakkai ronbunshu, 2018
In household refrigerators, the rotational speed of a reciprocating compressor can be appropriately adjusted according to the temperature inside of the refrigerator. The lower rotational speed reduces the power consumption of the compressor.
Ko INAGAKI   +4 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Effects caused by degeneration of natural frequency for pneumatic isolated table with two degrees-of-freedom

open access: yesNihon Kikai Gakkai ronbunshu, 2018
In this paper, it is confirmed that natural frequency of isolated table is operated and that degeneration, which means that some natural frequencies have the same value, has a bad influence. Pneumatic anti vibration apparatuses (AVAs) support that loaded
Yui AOKI, Shinji WAKUI
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1398-1419, June 2026.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Numerical Study of Frequency and Deflection Responses of Natural Fiber (Luffa) Reinforced Polymer Composite and Experimental Validation

open access: yesJournal of Natural Fibers, 2020
The natural fiber (Luffa cylindrica fiber) reinforced epoxy composite has been fabricated and their structural responses (frequency and deflection) have been computed experimentally and numerically first time using the corresponding experimental elastic ...
Hitesh B. Bisen   +5 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1591-1611, June 2026.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Improvement of natural frequency extraction in frequency domain

open access: yes, 2018
Natural Frequency extraction in the frequency domain using measured frequency responses is an ill-conditioned problem. A method is proposed to improve the accuracy of the previously extracted :natural frequencies. It is shown from results that the method
Lee, JH, Kim, HT
core   +1 more source

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