Results 41 to 50 of about 54,724 (267)
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
POSIADANIE A WŁASNOŚĆ NAD UWAGAMI ŚW. TOMASZA
Zeszyty Prawnicze, 2017 POSSESSION AND PROPERTY ON THE REMARKS OF ST. THOMAS AQUINAS Summary There are at least two of St. Thomas Aquinas’s questions which are of interest to a lawyer: whether possession is natural to a human being, and whether the keeping of goods as one’s ...
Franciszek Longchamps de Bérier
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FishesTo evaluate the potential biological effects of electromagnetic fields from offshore wind farms on Sebastes schlegelii, a laboratory-controlled chronic exposure experiment was conducted using a magnet-based static magnetic field system.
Tingting Wen +13 more
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FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
THE NATIONAL AND INTERNATIONAL IMPORTANCE OF THE DEVELOPMENT AND PLANNING OF RURAL SPACE - A VITAL PILLAR OF SUSTAINABLE DEVELOPMENT [PDF]
Scientific Papers Series : Management, Economic Engineering in Agriculture and Rural Development, 2023 The purpose of our article is to contribute with a complementary analysis to different conceptual and practical perspectives in relation to the approach, estimation and concrete evaluation of the classification of agricultural land, in direct relation to
Lucica DOBRE, Dorina Nicoleta MOCUŢA
doaj
Natural goodness without natural history [PDF]
Philosophy and Phenomenological Research, 2020 AbstractNeo‐Aristotelian ethical naturalism purports to show that moral evaluation of human action and character is an of evaluation ofnatural goodness—a kind of evaluation that applies to living things in virtue of their nature and based on their form of life.
openaire +1 more source