Results 51 to 60 of about 1,580,667 (265)

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

THE NORTHERN TERRITORIES OF WESTERN SIBERIA: DEMOGRAPHIC TRENDS AND GROWTH PARADOXES

Север и рынок: формирование экономического порядка
This paper analyzes socio-demographic trends over the past sixty years in the northern territories of Western Siberia, specifically the Khanty-Mansiysk and Yamalo-Nenets Autonomous Okrugs. The study spans from the initial development of mineral resources
Andrei G. Shelomentsev, Vladimir M. Kurikov, Kseniya S. Goncharova, Alina V. Istratii   +3 more
doaj   +1 more source

Pesticidal Activity of Sundarban Mangrove Plant Extracts against Sitophilus Pests and Identification of Active Constituents Using LC-MS

Advances in Pharmacological and Pharmaceutical Sciences, 2021
Plants act as a rich source of novel natural pesticides. In the backdrop of the recent revival of interest in developing plant-based insecticides, this study was carried out to investigate the pesticidal activity of Sundarban mangrove plants.
Md. Abdur Rahman, Rinku Rani Paul, Chaina Biswas, Hakima Akter, Razina Rouf, Sushmita Nath, Jamil A. Shilpi, Lutfun Nahar, Stayajit D. Sarker, Shaikh Jamal Uddin   +9 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Demographic Elements [PDF]

Revista Română de Sociologie, 2010
The author sets out to present the evolution of the population in Osica de Sus commune in the period between 1871 and 2009, with a focus on the evolution of the main demographic processes which occurred and continue to occur in the contemporary period.
ION PAUL POPESCU
doaj  

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Demographic potential of sex-age structure as a factor of population dynamics

Статистика и экономика, 2019
The study aims to assess the sex-age population structure in terms of its impact on the up-coming dynamics of natural increase and, consequently, on the general change in the population size.
Vladimir N. Arkhangelskiy, Yuliya V. Zinkina, Sergey G. Shulgin   +2 more
doaj   +1 more source

Molecular docking study of sea urchin (Arbacia lixula) peptides as multi-target inhibitor for non-small cell lung cancer (NSCLC) associated proteins. [PDF]

Journal of Pharmacy & Pharmacognosy Research, 2021
Context: Lung cancer is a type of cancer that causes the most deaths worldwide. The most common type of lung cancer is non-small cell lung cancer (NSCLC). Sea urchin (Arbacia lixula) has high potential as an anti-NSCLC agent.
Muhammad Hermawan Widyananda, Setyaki Kevin Pratama, Rizky Senna Samoedra, Fikriya Novita Sari, Viol Dhea Kharisma, Arif Nur Muhammad Ansori, Yulanda Antonius   +6 more
doaj  

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Holder continuity of bounded generalized solutions for nonlinear fourth-order elliptic equations with strengthened coercivity and natural growth terms

Electronic Journal of Differential Equations, 2017
In this article we extend the author's previous results on the existence of bounded generalized solutions of a Dirichlet problem for nonlinear elliptic fourth-order equations with the principal part satisfying a strengthened coercivity condition, and ...
Mykhailo V. Voitovych
doaj