Results 121 to 130 of about 859,723 (353)

Using OpenRefine for natural history collections data

open access: yes, 2022
OpenRefine (https://openrefine.org/) is a free, open source software for exploring and manipulating text data. As digitization and digital data management become increasingly important aspects of collections management, OpenRefine can be a useful tool to visualize data issues and to clean data efficiently.
Krimmel, Erica, Walker, Lindsay
openaire   +2 more sources

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini   +10 more
wiley   +1 more source

Toward a Comparative Cognitive History: Archimedes and D. H. J. Polymath [PDF]

open access: yesarXiv, 2012
Is collective intelligence just individual intelligence writ large, or are there fundamental differences? This position paper argues that a cognitive history methodology can shed light into the nature of collective intelligence and its differences from individual intelligence.
arxiv  

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu   +15 more
wiley   +1 more source

Crossing the Caucasus hunting for plants: the collection itinerary of the botanists Stéphen Sommier and Émile Levier in the summer of 1890

open access: yesJournal of Maps
Stéphen Sommier and Émile Levier were eminent botanists and plant collectors (but also ethno-anthropologists, geographers and photographers), best known for their scientific travels in Italy and abroad.
Daniele Viciani   +3 more
doaj   +1 more source

Patterns of divergence in fish species separated by the Isthmus of Panama

open access: yesBMC Evolutionary Biology, 2017
Background The Pleistocene closure of Isthmus of Panama, separating the basins of the Eastern Pacific and the Caribbean Sea, created a unique natural experiment that reveals how marine faunas respond to environmental change.
Christine E. Thacker
doaj   +1 more source

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu   +11 more
wiley   +1 more source

The discovery of superfluidity [PDF]

open access: yes, 2006
Superfluidity is a remarkable manifestation of quantum mechanics at the macroscopic level. This article describes the history of its discovery, which took place at a particularly difficult period of the twentieth century. A special emphasis is given to the role of J.F. Allen, D. Misener, P. Kapitza, F. London, L. Tisza and L.D. Landau.
arxiv   +1 more source

Bibionidae and Pipunculidae of the Philippines and Bismarck Islands (Diptera) [PDF]

open access: yes, 2011
This stndy is based largely upon collections from the Danish Noona Dan Expedition to the southern Philippines and the Bismarck Islands (Pelersen, 1966), supplemented with collections from the B. P. Bishop Museum, British Museum (Natural History), U.
Hardy, D. Elmo
core  

Gauging the current status of natural history collections in Malaysia [PDF]

open access: yes, 2019
This study was carried out to gauge the current status of natural history collection centres in Malaysia, primarily focused on animal collections. Part of the research is reported here and it constituted objective one which is to compare the status of ...
  +9 more
core   +1 more source

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