Results 101 to 110 of about 554,182 (299)

Fossil bears break free from inhibitory cascade constraints at least twice (Ursus minimus and Ursus deningeri) caused by dietary adaptations

Boreas
The inhibitory cascade model (ICM) predicts relative mammalian molar size and shows a relationship between relative molar size and diet. Bears do not follow the ICM.
Anneke H. vanHeteren, A. Stefanie Luft
doaj   +1 more source

Patterns of divergence in fish species separated by the Isthmus of Panama

BMC Evolutionary Biology, 2017
Background The Pleistocene closure of Isthmus of Panama, separating the basins of the Eastern Pacific and the Caribbean Sea, created a unique natural experiment that reveals how marine faunas respond to environmental change.
Christine E. Thacker
doaj   +1 more source

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source

Crossing the Caucasus hunting for plants: the collection itinerary of the botanists Stéphen Sommier and Émile Levier in the summer of 1890

Journal of Maps
Stéphen Sommier and Émile Levier were eminent botanists and plant collectors (but also ethno-anthropologists, geographers and photographers), best known for their scientific travels in Italy and abroad.
Daniele Viciani, Lorella Dell’Olmo, Chiara Nepi, Lorenzo Lastrucci   +3 more
doaj   +1 more source

Notes on Littorina saxatilis and allied shells examined at the British Museum of Natural History, London [PDF]

, 1988
This short note records some notes made by the author on the shells of Littorim saxatllis (Olivi) and certain allied forms while examining these from collections in the British Museum of Natural History ...
Seshappa, G
core  

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Additional Vertebrate Records and Natural History Notes from Arkansas [PDF]

, 2013
Although vertebrates are a commonly studied group of animals, the distribution and natural history of many species within Arkansas is still not well understood or documented.
Connior, M. B., McAllister, C. T., Placyk, J. S., Jr., Robison, H. W., Tumlison, C. Renn   +4 more
core   +2 more sources

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source