Results 91 to 100 of about 554,182 (299)

Digitization and the future of natural history collections [PDF]

open access: yesBioScience, 2019
Natural history collections (NHCs) are the foundation of historical baselines for assessing anthropogenic impacts on biodiversity. Along these lines, the online mobilization of specimens via digitization–the conversion of specimen data into accessible digital content–has greatly expanded the use of NHC collections across a diversity of disciplines.
Brandon P Hedrick   +11 more
openaire   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Age Estimation using Phalangeal Skeletochronology in Northern Crawfish Frogs, Lithobates areolatus circulosus (Amphibia: Anura: Ranidae), from Arkansas [PDF]

open access: yes, 2019
As an obligate crayfish burrow dweller, crawfish frogs have historically occupied a relatively narrow ecological niche throughout their distribution in the tall grass prairies and grasslands of the central and south-central United States.
Thigpen, Christopher S.   +1 more
core   +3 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

The MIAmaxent R package: Variable transformation and model selection for species distribution models

open access: yesEcology and Evolution, 2019
The widely used “Maxent” software for modeling species distributions from presence‐only data (Phillips et al., Ecological Modelling, 190, 2006, 231) tends to produce models with high‐predictive performance but low‐ecological interpretability, and ...
Julien Vollering   +2 more
doaj   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Zoo Store 1 at the Natural History Museum: Meeting National Standards [PDF]

open access: yes, 2007
The Natural History Museum (NHM), London is at the forefront of natural history science, and a major player in developing standards for the care of these collections in museums. Around ten years ago, there was a great deal of activity developing policies
Carnall, M
core  

NATURAL HISTORY AND BIOGEOGRAPHY OF THE AMPHIBIANS AND REPTILES OF KIBALE NATIONAL PARK, UGANDA [PDF]

open access: yes, 2001
This study lists the amphibian and reptile species of Kibale National Park, Uganda, and discusses the natural history and biogeography of this unique herpetofauna.
Vonesh, James
core   +2 more sources

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

open access: yesFEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

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