Results 61 to 70 of about 17,223,689 (245)
Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription
FEBS Open Bio, EarlyView.In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang +10 more
wiley +1 more source
Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model
FEBS Open Bio, EarlyView.This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito +7 more
wiley +1 more source
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
FEBS Open Bio, EarlyView.Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
Image denoising with directional bases [PDF]
, 2007 Directional information is an important component of both natural and synthetic images, and it is exploited in many image processing applications. Directional basis analysis is used to capture significant structural information.
Park, Heechan +3 more
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IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing, 2020 Accurate and reliable greenhouse mapping using remotely sensed data and image classification methods has a significant role since it can comprehensively improve the urban and rural planning, and sustainable natural resource and agricultural management ...
Filiz Bektas Balcik +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti +5 more
wiley +1 more source
E-yearbook of Food and Natural Resource Statistics for 2018 [PDF]
, 2019 This is the fourth time the E-yearbook of Food and Natural Resource Statistics of the Natural Resources Institute Finland (Luke) has been published.
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Image statistics substantiate Gaudí’s naturalistic design principles
Scientific ReportsHuman observers perceive natural and man-made environments differently, a distinction measurable through image statistics. However, limited evidence exists on how architectural style influences these statistics and, consequently, visual perception ...
Olga Dyakova +2 more
doaj +1 more source
Sensors, 2020 Like natural images, remote sensing scene images; of which the quality represents the imaging performance of the remote sensor, also suffer from the degradation caused by imaging system.
Ningshan Xu +3 more
doaj +1 more source
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
FEBS Open Bio, EarlyView.GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source