Results 101 to 110 of about 12,793,653 (323)
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Sub-Natural Linewidth Single Photons from a Quantum Dot
The observation of quantum dot resonance fluorescence enabled a new solid-state approach to generating single photons with a bandwidth almost as narrow as the natural linewidth of a quantum dot transition.
Anthony Nickolas Vamivakas +3 more
core +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Exploring the Impact of Natural Light Exposure on Sleep of Healthy Older Adults: A Field Study
Studies among people with dementia demonstrated that the sleep quality and rhythm improves significantly when people are exposed to ambient bright light.
M. Aarts +3 more
semanticscholar +1 more source
Long-Range Imaging through Scattering Media Using Deep Learning
Imaging through scattering media is an important and challenging problem, and the technology has been used in many fields, such as autonomous driving, industrial inspections, remote sensing imaging, and biomedical imaging.
Ying Jin, Cangtao Zhou, Wanjun Dai
doaj +1 more source
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
Photoelectric detection system [PDF]
A photoelectric beam system for the detection of the arrival of an object at a discrete station wherein artificial light, natural light, or no light may be present is described.
Currie, J. R., Schansman, R. R.
core +1 more source
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Characterisation of the mechanical and thermal degradation behaviour of natural fibres for lightweight automotive applications [PDF]
It is well established that light-weighting of automotive parts leads to reduced carbon emissions over vehicle lifetime. Mineral fibres and fillers have a relatively high density and may require high levels of energy in their production, resulting in a ...
Liggat, John +3 more
core

