Results 121 to 130 of about 12,793,653 (323)

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

PolyArch

Spool, 2015
The challenge of the future is to minimize the energy consumption of buildings while maintaining an optimal comfort level in the interior. Controlling the energy streams in and out of the building , and especially daylight management, plays an important ...
Eric van den Ham, Truus Hordijk, Tillmann Klein, Jan Hensen, Alexander Rosemann, Albert Schenning, Michael Debije   +6 more
doaj   +1 more source

Tetramixing of vector and pseudoscalar mesons: A source of intrinsic quarks

, 2011
The tetramixing of pseudoscalar mesons $\pi$-$\eta$-$\eta'$-$\eta_c$ and vector mesons $\omega$-$\rho$-$\phi$-$J/\psi$ are studied in the light-cone constituent quark model, and such mixing of four mesons provides a natural source for the intrinsic charm
Bo-Qiang Ma, L. van Elfrinkhof, L. A. Kondratyuk, L. A. Kondratyuk, M. Gell-Mann, S. J. Brodsky, S. J. Brodsky, Tao Peng, W. Pauli, Z.-Q. Ma   +9 more
core   +1 more source

Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node

FEBS Open Bio, EarlyView.
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner, César G. Prucca, Lucia Boffelli, Virginia A. Piqueras, Silvia G. Correa, Mariana Maccioni, Mario E. Guido   +6 more
wiley   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Photochemically responsive polymer films enable tunable gliding flights

Nature Communications
Miniaturized passive fliers based on smart materials face challenges in precise control of shape-morphing for aerodynamics and contactless modulation of diverse gliding modes.
Jianfeng Yang, M. Ravi Shankar, Hao Zeng
doaj   +1 more source

Data on chemical composition of alkaloids of Plumula nelumbinis and antioxidant activity from thirteen habitats in China

Data in Brief, 2018
Plumula nelumbinis is widely consumed as tea for its pharmacological properties, which is related to its chemical composition, so the identification of the major compounds of P. nelumbinis is valuable.
Wenyue Tian, Hui Zhi, Chao Yang, Likang Wang, Jiatang Long, Luomin Xiao, Jizheng Liang, Ying Huang, Xi Zheng, Suqing Zhao, Kun Zhang, Junxia Zheng   +11 more
doaj   +1 more source

Measurements of the Cerenkov light emitted by a TeO2 crystal

, 2012
Bolometers have proven to be good instruments to search for rare processes because of their excellent energy resolution and their extremely low intrinsic background.
Bellini, F., Casali, N., Dafinei, I., Marafini, M., Morganti, S., Orio, F., Pinci, D., Vignati, M., Voena, C.   +8 more
core   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source