Results 61 to 70 of about 5,147,211 (291)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Modern aspects of photodynamic therapy of actinic keratoses

open access: yesBiomedical Photonics, 2019
Currently, photodynamic therapy (PDT) remains the most effective treatment for actinic keratosis (AK). With the increase in the incidence of AK, mainly due to the popularization of recreation in countries with increased insolation, there is an increasing
I. V. Reshetov   +8 more
doaj   +1 more source

On the Tuning and the Mass of the Composite Higgs [PDF]

open access: yes, 2012
We analyze quantitatively the tuning of composite Higgs models with partial compositeness and its interplay with the predicted Higgs mass. In this respect we identify three classes of models, characterized by different quantum numbers of the fermionic ...
Panico, Giuliano   +3 more
core   +2 more sources

On the Nature of Light [PDF]

open access: yesProceedings of the National Academy of Sciences, 1926
In a recent article in these Proceedings (1) Professor G. N. Lewis has suggested that the conflict between the quantum theory of light and the known facts of interference might be resolved by assuming that an atom never emits a quantum of light except to another atom, the possibility of transmission of the quantum being determined by the nature of the ...
R C, Tolman, S, Smith
openaire   +2 more sources

A naturally light Higgs without light top partners [PDF]

open access: yesJournal of High Energy Physics, 2015
ISSN:1029 ...
Carmona Adrian, Goertz Florian
openaire   +3 more sources

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Molecular Response in One-Photon Absorption via Natural Thermal Light vs Pulsed Laser Excitation

open access: yes, 2012
Photoinduced biological processes occur via one photon absorption in natural light, which is weak, CW and incoherent, but are often studied in the laboratory using pulsed coherent light.
Cheng   +21 more
core   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Natural light as a determinant of the identity of architectural space

open access: yesJournal of Architecture and Urbanism, 2014
In this study, the effect of natural light on the architectural space quality was examined. Contribution of natural light in three different dimensions as the readability of the space, the effect of the space, and its aesthetical evaluation was taken ...
Ilker Fatih Ozorhon, Turkan Ulusu Uraz
doaj   +1 more source

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