Results 181 to 190 of about 4,658,191 (250)

Alterations to longitudinal muscle morphology and mechanical function following immobilization and recovery in female ovariectomized and intact rats

open access: yesExperimental Physiology, EarlyView.
Abstract Serial sarcomere number (SSN) is reduced following immobilization of a muscle in a shortened position in male rodents thereby impairing muscle contractile function. However, in female rodents the effects of oestrogen on SSN and mechanical changes following immobilization and re‐ambulation are unknown.
Alexandra Q. Kirkup   +3 more
wiley   +1 more source

Brain strain: Blood flow and metabolism in environmental extremes

open access: yesExperimental Physiology, EarlyView.
Abstract This narrative review compares and contrasts the most commonly encountered environmental stressors on human cerebrovascular functioning. From high altitude and space, extreme apnoea, heat and cold stress, the impact of these stressors on the regulation of cerebral blood flow (CBF) and oxygen metabolism (CMRO2${\mathrm{CM}}{{\mathrm{R}}_ ...
Dario Vrdoljak   +3 more
wiley   +1 more source

Microvascular endothelial function is blunted in postmenopausal females with frequent hot flushes

open access: yesExperimental Physiology, EarlyView.
Abstract Hot flushes of menopause are associated with elevated blood pressure (BP) and diminished macrovascular endothelial function, an initiating factor in the onset of atherosclerosis. Whether microvascular endothelial function is impaired in females with hot flushes, however, remains unknown.
William Stokes   +9 more
wiley   +1 more source

Musculoskeletal decay and bone–muscle crosstalk during physical disuse: Mechanisms and integrated countermeasures

open access: yesExperimental Physiology, EarlyView.
Abstract Older adults experience a markedly increased risk of falls and fractures following hospital discharge, largely due to the rapid musculoskeletal deterioration associated with bed rest. Although age‐related muscle and bone loss typically develops gradually, acute physical inactivity accelerates key biological processes underlying sarcopenia and ...
Julia Margarita Reyes   +5 more
wiley   +1 more source

Distribution of age at natural menopause, age at menarche, menstrual cycle length, height and BMI in BRCA1 and BRCA2 pathogenic variant carriers and non-carriers: results from EMBRACE. [PDF]

open access: yesBreast Cancer Res
Mavaddat N   +33 more
europepmc   +2 more sources

Ovariectomy, but not moderate intermittent hypoxia, promotes respiratory instability and risk of obesity in adult female rats

open access: yesExperimental Physiology, EarlyView.
Abstract Sleep apnoea (SA) is a prevalent and complex respiratory disorder associated with recurrent interruptions of air flow during sleep. SA causes sleep fragmentation and intermittent hypoxia which leads to numerous negative health consequences.
Marianne Gagnon   +5 more
wiley   +1 more source

Age at natural menopause impacts cerebrovascular reactivity and brain structure.

open access: yesAm J Physiol Regul Integr Comp Physiol, 2023
Moir ME   +11 more
europepmc   +1 more source

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