Results 211 to 220 of about 4,658,191 (250)

SURMOUNT‐REAL UK: A Pragmatic Randomized Clinical Trial to Assess the Effectiveness of Tirzepatide in Adults With Obesity

open access: yesObesity, Volume 34, Issue 11, Page 2051-2060, November 2026.
ABSTRACT Objective SURMOUNT‐REAL UK will evaluate the effectiveness of tirzepatide when offered in addition to standard‐of‐care (SoC) in adults with Class I obesity (BMI ≥ 30 and ≤ 34.9 kg/m2) and without diabetes in a UK primary care setting. Methods A 5‐year, phase 4, multicenter, open‐label, pragmatic randomized clinical trial is enabled through ...
Martin K. Rutter   +14 more
wiley   +1 more source

Pharmacological and Therapeutic Potential of Garlic (Allium sativum): Integrating Phytochemistry, Molecular Mechanisms, and Clinical and Preclinical Evidence

open access: yesChemistryOpen, Volume 15, Issue 11, November 2026.
Garlic bioactive compounds, including organosulfur compounds (allicin, DADS, DATS, and SAC), phenolic compounds, and quercetin, regulate the Nrf2/HO‐1, NF‐κB, PI3K/Akt, and AMPK/eNOS signaling pathways. These actions enhance antioxidant defenses, suppress inflammation, improve metabolic and cardiovascular function, and contribute to reduced blood ...
Gudisa Bereda
wiley   +1 more source

Obscured Rhythms: Using Rhythmanalysis to Understand How Symptoms Associated With Menopause Shape Everyday Experiences of Physical Activity

open access: yesSociology of Health &Illness, Volume 48, Issue 8, November 2026.
ABSTRACT Physical activity (PA) is frequently promoted as a means of managing symptoms associated with the menopause transition (MT), yet little is known of how the embodied, emotional and temporal disruptions of menopause influence the experiences of, and possibilities for, movement.
Cassandra Phoenix   +2 more
wiley   +1 more source

The Impact of Heavy Menstrual Bleeding on Quality of Life: A Mixed‐Methods Survey Study

open access: yesBJOG: An International Journal of Obstetrics &Gynaecology, Volume 133, Issue 12, Page 2170-2177, November 2026.
ABSTRACT Objective To examine the physical, psychological, social, and functional impact of heavy menstrual bleeding (HMB) using a mixed‐methods approach. Design Mixed‐methods online survey. Population A UK‐wide sample of adults assigned female at birth with lived experience of HMB.
Michalina Drejza   +8 more
wiley   +1 more source

Age at natural menopause and associated factors with early and late menopause among Chinese women in Zhejiang province: A cross-sectional study. [PDF]

open access: yesPLoS One
Jiao J   +13 more
europepmc   +1 more source

Edible Biopolymer Coatings for Postharvest Preservation in Warm‐Chain Horticultural Supply Chain: Mechanisms, Materials, Design Strategies, and Future Directions

open access: yesComprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 6, November 2026.
ABSTRACT Fresh fruit and vegetable postharvest losses reach 30%–50% between harvest and consumption, concentrated in low‐ and middle‐income countries where warm‐chain supply chains (20°C–35°C, 55%–85% relative humidity, intermittent handling) replace the refrigerated cold chains conventional technology assumes.
Olaoluwa Omoniyi Olarewaju   +1 more
wiley   +1 more source

Genome Aging in Women: Hematopoietic Loss of X Chromosome as An Exemplar

open access: yesAging Cell, Volume 25, Issue 11, November 2026.
As studies at the intersection of genetics and aging are rapidly advancing, genome aging provides a novel mechanism by which aging phenotypes occur. In this Review, the authors examine the rise, expansion, and the consequences of X chromosome loss in female blood cells.
Xihan Guo, Xueqin Dai
wiley   +1 more source

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