Results 41 to 50 of about 2,600 (213)

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Seasonal movements of adult Gizzard Shad Dorosoma cepedianum in a Missouri River reservoir

Journal of Freshwater Ecology
Gizzard Shad Dorosoma cepedianum are important for nutrient cycling and can affect water clarity, plankton densities, and fish production levels. Gizzard Shad can also be crucial prey fish for recreationally important species such as Walleye Sander ...
Kayla M. Reed, Justin A. VanDeHey, Hilary A. Morey, Robert P. Hanten, Elizabeth A. Renner, Mark J. Fincel   +5 more
doaj   +1 more source

Upravljanje gorskih nevarnosti in tveganj v zavarovanih območjih: primer triglavskega narodnega parka, Slovenija ; alpine hazard and risk management in protected areas: the case of the triglav national park, Slovenia [PDF]

Geodetski Vestnik, 2013
Regionalni in prostorski razvoj Slovenije temelji na velikem deležu zavarovanih območij, ki prinašajo posebne zahteve za prostorske planerje. Za ponazoritev povezave med planiranjem v prostoru in upravljanjem zavarovanih območij v prispevku obravnavamo ...
Matjaž Mikoš
doaj  

MONITORING OF THE TOURIST-RECREATIONAL ACTIVITY OF SPECIALLY PROTECTED NATURAL TERRITORIES AS AN EFFECTIVE INDICATOR OF PREDICTED DEVELOPMENT OF TOURIST TERRITORIES

Юг России: экология, развитие, 2019
Aim. The main aim is to determine the effectiveness of using the monitoring of tourist and recreational activities as an indicator in forecasting the development of a tourist territory using the example of specially protected natural areas of the ...
Nikolay V. Vishnyakov, Olga Y. Zelenskaya   +1 more
doaj   +1 more source

The Characteristics of German Natural Park System: A Case in Saar-Hunsrueck Natural Park

Journal of The Japanese Institute of Landscape Architecture, 2003
The aim of this research is to examine the characteristics of German natural park system from the comparative viewpoint with Japanese natural park system. Saal-Hunsruck Natural Park was surveyed as a study area. It was found that German natural park system doesn’t have any regulations for land use although the purpose of natural park is to protect ...
openaire   +2 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

First checklist on the amphibians and reptiles of Mount Korbu, the second highest peak in Peninsular Malaysia [PDF]

Check List, 2019
This study represents the first report on the amphibians and reptiles of Mount Korbu, the highest peak in the Titiwangsa Range (2182 m a.s.l.) and the second highest peak in Peninsular Malaysia.
Kin Onn Chan, Mohd Abdul Muin, Shahrul Anuar, Joel Andam, Norazlinda Razak, Mohd Azizol Aziz   +5 more
doaj   +3 more sources

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

A Study of natural radioactivity in urban parks

HNPS Advances in Nuclear Physics
Urban parks are typically undisturbed natural locations inside metropolitan areas, attracting human recreation activities. The present work focuses on studying the radioactivity levels in urban parks in the metropolitan areas of Athens, Barcelona, and Bucharest to establish a baseline of the overall environmental load and the associated contribution to
Foivos Panagiotis Gelatsoras, Theo Mertzimekis, Pavlos Krassakis, Varvara Lagaki, Ioannis Madesis, Georgios Siltzovalis   +5 more
openaire   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source