Results 91 to 100 of about 22,798 (265)

Disruption of the SNRPF–DDX24–E2F4 Feedback Loop Uncouples Splicing and Transcriptional Regulation to Suppress Ovarian Cancer Progression

open access: yesAdvanced Science, EarlyView.
This study identifies SNRPF as a critical oncogenic driver in ovarian cancer. By regulating a self‐sustaining SNRPF–DDX24–E2F4 feedback loop through intron retention and nonsense‐mediated decay, SNRPF couples RNA splicing with transcriptional regulation to promote tumor progression.
Yingwei Li   +4 more
wiley   +1 more source

Valuation of livestock population and national feed security to enhance livestock productivity in Ethiopia

open access: yesVeterinary Medicine and Science
Background Feed is a major input in the livestock industry and covers about 60%–70% of the total cost of producing meat, milk and eggs. Inadequate feed supply in terms of quality and quantity leads to lower production performance in livestock.
Regasa Begna, Worku Masho
doaj   +1 more source

Manejo de novilhas prenhes aos 13/15 meses de idade em sistemas a pasto Pregnant heifers management at 13/15 months of age in grazing systems

open access: yesRevista Brasileira de Zootecnia, 2008
O trabalho foi realizado para avaliar o desenvolvimento de 32 novilhas primíparas gestantes Aberdeen Angus e mestiças Angus recriadas e acasaladas dos 13 aos 15 meses de idade.
Alcides Pilau   +1 more
doaj   +1 more source

Harnessing Phase Separation for the Development of High‐Performance Hydrogels

open access: yesAdvanced Science, EarlyView.
ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao   +3 more
wiley   +1 more source

Wide Temperature Zero Thermal Expansion in Al Matrix Composites with High Thermal Conductivity

open access: yesAdvanced Science, EarlyView.
Strain engineering strategy is implemented on the negative thermal expansion (NTE) phase Zn1.6Mg0.4P2O7 within composites, where Al matrix‐induced compressive strain drives uniform polyhedral and unit cell evolution, thereby enabling broad and consistent thermal compensation efficacy and obtaining good thermal performance.
Jinrui Qian   +14 more
wiley   +1 more source

Renal IGFBP6 Interacts With THBS1 to Drive Renal Cellular Senescence and Fibrosis

open access: yesAdvanced Science, EarlyView.
ABSTRACT Epithelial dedifferentiation and myofibroblast activation are critical drivers of chronic kidney disease (CKD) progression. Elevated levels of IGFBP6 have been linked to decreased renal function in CKD patients, but its precise role and underlying mechanisms remain unclear.
Ju‐tao Yu   +26 more
wiley   +1 more source

Interpretable Machine Learning Framework for Nb─Si Based Alloy Design with Enhanced Fracture Toughness

open access: yesAdvanced Science, EarlyView.
An interpretable machine learning framework integrating SHAP and PDP analysis identifies critical design descriptors from 139 physicochemical features for Nb─Si alloys. The framework achieves <7% prediction error and guides the discovery of Nb38.5Ti38.5Si3Zr18V2 alloy with 22.791 MPa·m1/2 fracture toughness, breaking the 20 MPa·m1/2 barrier.
Dezhi Chen   +7 more
wiley   +1 more source

Enhancing Biological Nitrogen Fixation Through Diverse Pasture Swards

open access: yesPlants
Regenerative agricultural practices emphasize the use of diverse pasture species within sustainable agriculture production systems. The inclusion of a range of legume species in diverse pasture swards is likely to increase biological N fixation (BNF ...
Rukshagini Sutharsan   +6 more
doaj   +1 more source

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