Results 91 to 100 of about 8,636,926 (272)

Preliminary prospects of assessment using telemetry in the study of gerbils’ mobility in natural plague focus

International Journal of Biology and Chemistry, 2015
The article shows that a relatively quick obtaining direct and most importantly absolutely accurate data on individual movements of marked individuals, based on field research in 2012-2014 makes telemetry a very promising direction in mobility study of the potential plague hosts in natural focus of this infection.
L. A. Burdelov, A. B. Eszhanov, N. Hughes, S. T. Nurtazin, Leirs Herwig, A. M. Baibagyssov   +5 more
openaire   +1 more source

A Small‐Molecule DEPTAC Rescues Cognitive Deficits by Targeted Dephosphorylation of Pathological Tau

Advanced Science, EarlyView.
TP2 is a fully synthetic small‐molecule dephosphorylation‐targeting chimera that recruits endogenous PP2A‐Bα to Tau, enabling targeted removal of pathological phosphate modifications. In two tauopathy mouse models, systemic TP2 reduces Tau pathology, preserves neuronal and synaptic integrity, improves neuroimmune homeostasis, and rescues cognition ...
Fei Sun, Yang Liu, Qiuzhi Zhou, Qingyuan Hu, Weixia Wang, Yue Xiao, Jingfen Su, Guanting Liu, Miaomiao Sun, Lixia Chen, Hua Li, Ying Yang, Jian‐Zhi Wang   +12 more
wiley   +1 more source

Dual‐line Genome‐scale CRISPR Screening Enables Robust Target Gene Discovery

Advanced Science, EarlyView.
A species‐optimized CRISPR platform integrates efficient piggyBac delivery, genome‐scale sgRNA libraries, and parallel screening in two independently engineered Bactrocera dorsalis Cas9 cell lines. Cross‐line consensus analysis filters line‐specific effects, enriches candidates with reproducible in vivo phenotypes, and reveals conserved, species ...
Ziniu Li, Jiao Qiao, Qiuyuan Zhang, Peipei Liu, Chenjun Zheng, Qi Zhou, Mengqi Ji, Zhihui Zhu, Xiaoxue Li, Hongyu Zhang   +9 more
wiley   +1 more source

MONITORING OF VACCINAL PROCESS IN HUMANS RESIDING IN THE ALTAI HIGH-MOUNTAINOUS NATURAL PLAGUE FOCUS

Russian Journal of Infection and Immunity, 2018
.
K. M. Korytov, S. V. Balakhonov, V. V. Voitkova, V. I. Dubrovina, A. K. Noskov, A. I. Mishchenko, L. V. Shchuchinov, A. A. Makin   +7 more
openaire   +3 more sources

Tailored Covalent Organic Frameworks Enable the Encapsulation of Living Cells to Produce Rare Ginsenoside

Advanced Science, EarlyView.
This work reports the in situ fabrication of Escherichia coli@covalent organic frameworks (E. coli@COFs) in phosphate‐buffered saline. The COFs form an exoskeleton on E. coli, protecting intracellular β‐glucosidase (Ssbgl) while enhancing mass transfer.
Fengmei Liu, Shan Zhang, Shanrong Wei, Ziye Xing, Hongming He, Xiao Liang, Quanshun Li   +6 more
wiley   +1 more source

EVALUATION OF PLAGUE EPIZOOTIC CONDITION OF PREARAL-QARAQYM PLAGUE FOCUS OF KAZAKHSTAN IN SPRING AND SUMMER TIME OF 2013

Acta Biomedica Scientifica, 2015
In the Republic of Kazakhstan, there a re the natural plague foci. For the analysis, the passport data of plague epizooty activity in the PreAral-Qaraqym plague focus of Qyzylorda Province were collected.
Z. A. Sagiyev, Z. Z. Abdel, A. A. Abdirasilova, R. S. Mussagaliyeva, A. M. Matzhanova, G. N. Yermekov, M. Z. Bodykov, I. S. Ilyasova, B. K. Moldabekov, T. S. Alzhanov, Z. O. Yesmaganbetov, M. U. Burambayeva, G. M. Burkhanova, N. A. Zhaniyazov   +13 more
doaj  

Sanitary-educational activities as an effective method of nonspecific plague prevention in the natural plague focus in the kosh-agach district of the Republic of Altai

Health Risk Analysis
The Altai Mountains are an area of ecological tourism with high potential for further development. At the same time, intensive epizootics of plague are typical for the region including those registered in close proximity to settlements and shepherds’ camps raising likelihood of potential contacts between people and plague vectors and carriers ...
S.V. Balakhonov, E.S. Kulikova, A.I. Mishchenko, V.M. Korzun, A.V. Rogaleva, S.M. Lyashenko, A.A. Itashev, S.L. Sarikova, N.B. Kalybayeva   +8 more
openaire   +2 more sources

Inverse Design of Pre‐Strain via a Predictive Electromechanical Model for Enhanced Strain Sensing

Advanced Science, EarlyView.
An analytical electromechanical model rooted in microcrack evolution mechanics is globally calibrated from only eight pre‐strain datasets, enabling prediction of the complete sensing response at untested pre‐strain values within the calibrated design space (R2 > 0.99).
Jia‐Chen Shang, Rui Wang, Bo Lu, Ming‐Liang Song, Yu‐Yi Chen, Kuo Han, Xin‐Jie Feng, Bin Sun, Yao‐Guang Cao, Xiao‐Yu Yan, Shi‐Chun Yang   +10 more
wiley   +1 more source

Results of Epizootiological Survey of the Mongolian Part of Trans-Baikal Steppe Natural Plague Focus in 2017 [PDF]

, 2017
Objective of the study is to obtain the data on the state of Severokerulensky plague focus in Mongolia, adjacent to the Trans-Baikal steppe focus in the south.
M. B. Sharakshanov, Ts. Uuganbayar, Ch. Erdenechimeg, E. A. Vershinin, D. Tserennorov, N. G. Revenskaya, B. Byambazhav, S. V. Balakhonov, A. B. Moshkin, I. M. Makhinova, L. Erdenechimeg, Ts. Gankhuyag, N. Tsogbadrakh, S. A. Kosilko, D. Gandbold   +14 more
core   +1 more source

Asymmetric Evolution of Antennal Cell Types Underlies a Derived Ammonia‐Sensing Logic for Ecological Adaptation in Bactrocera dorsalis

Advanced Science, EarlyView.
Comparative antennal single‐nucleus transcriptomics reveals cell‐type‐dependent transcriptomic divergence in Bactrocera dorsalis, with similar structural cells but divergent sensory neurons. This neuronal diversification is associated with a distinct ammonia‐sensing pathway, linking female attraction to bird‐dropping‐associated cues with nutritional ...
Wei Liu, Shuai Zhang, Jie Zhang, Zhen Tian, Yuanbo Xue, Ling Yang, Jun Xu, Guirong Wang   +7 more
wiley   +1 more source