Results 51 to 60 of about 953,637 (258)
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
DiversityA newly discovered rust fungus poses a significant threat to the survival and reproduction of the endangered plant Cystopteris chinensis in a forest in western Sichuan province, China.
An Yu, Xia Zhao, Xiaohong Chen
doaj +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Assessing expandable Global Positioning System collars for moose neonates
Wildlife Society Bulletin, 2018 Deploying Global Positioning System (GPS) collars on ungulate neonates would offer notable advantages to examining their life history and influence on population performance.
Tyler R. Obermoller +2 more
doaj +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
SPATIAL HANDLING OF WILD TURKEY SURVEY DATAUSING GEOGRAPHIC INFORMATION SYSTEM MAPPING PROCEDURES
Wildlife Society Bulletin, 1995 : We describe analysis and mapping procedures for a wild turkey (Meleagris gallopavo silvestris) survey using turkey sightings by deer hunters. Population indices developed from randomly collected turkey observation data were summarized by turkey ...
Richard O. Kimmel +2 more
doaj +1 more source
Distributed population protocols: naturally! [PDF]
, 2021 Classical population protocols manage a fix size population of agents that are created by the input population: one agent exactly per unit of the input. As a consequence, complex protocols that have to perform several independent tasks find here a clear bottleneck that drastically reduces the parallelism in the execution of those tasks.
openaire +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Frontiers in Ecology and Evolution, 2020 The bank vole has become an important species for the study of gene expression changes underlying evolutionary adaptation, within-host dynamics and resistance to pathogens, or response to pollutants.
Lucie Němcová +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source