Results 71 to 80 of about 953,637 (258)

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Estimating the Degree of Polyandry in Natural Populations [PDF]

open access: yesEvolution, 1981
A mating system in which one dominant male sires all the offspring implies that a deme practicing it has a small effective size. A group of isolated demes with this mating system would become more genetically divergent in time due to genetic drift alone.
openaire   +2 more sources

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

open access: yesFEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu   +10 more
wiley   +1 more source

Development and Application of EST-SSR Markers to Assess Genetic Diversity and Structure of Eleutherococcus senticosus for Conservation and Breeding

open access: yesPlants
Eleutherococcus senticosus, a medicinally important woody plant, is widely used in pharmaceuticals and functional foods due to its bioactive compounds. Its wild populations are facing severe threats due to over-harvesting.
Shikai Zhang   +9 more
doaj   +1 more source

Position Effects in Natural Populations

open access: yesThe American Naturalist, 1954
Uploaded by Plazi for TaxoDros. We do not have abstracts.
openaire   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Correlation of pedunculate oak leaf traits in situ and ex situ in Bosnia and Herzegovina

open access: yesFolia Oecologica
Pedunculate oak is an economically and ecologically very valuable species at the European level and for Bosnia and Hercegovina, and research into variation of this species is very important.
Hodžić Mirzeta Memišević   +2 more
doaj   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

The Genetic Architecture of Arabidopsis thaliana in Response to Native Non-Pathogenic Bacterial Species Revealed by Genome-Wide Association Mapping in Field Conditions

open access: yesPhytobiomes Journal
Non-pathogenic bacteria can substantially contribute to plant health by mobilizing and supplying nutrients, providing protection against pathogens, and alleviating abiotic stresses.
Daniela Ramírez-Sánchez   +5 more
doaj   +1 more source

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