Results 121 to 130 of about 1,189,605 (351)
FEBS Open Bio, EarlyView.Mitochondria‐associated membranes (MAMs) are contact sites between the endoplasmic reticulum and mitochondria that regulate calcium signaling, lipid metabolism, autophagy, and stress responses. This review outlines their molecular organization, roles in cellular homeostasis, and how dysfunction drives neurodegeneration, metabolic disease, cancer, and ...
Viet Bui +3 more
wiley +1 more source
Active invasion of bacteria into living fungal cells
eLife, 2014 The rice seedling blight fungus Rhizopus microsporus and its endosymbiont Burkholderia rhizoxinica form an unusual, highly specific alliance to produce the highly potent antimitotic phytotoxin rhizoxin.
Nadine Moebius +4 more
doaj +1 more source
Foeniculum vulgare Essential Oils: Chemical Composition, Antioxidant and Antimicrobial Activities [PDF]
, 2010 The essential oils from Foeniculum vulgare commercial aerial parts and fruits were isolated by hydrodistillation, with different distillation times (30 min, I h, 2 h and 3 h), and analyzed by GC and GC-MS. The antioxidant ability was estimated using four
Barroso, J. G. +6 more
core
Facile synthetic procedure for and electrochemical properties of hexa(2-thienyl)benzenes directed toward electroactive materials [PDF]
, 2008 In the presence of RhCl3 center dot 3H(2)O and i-Pr2NEt, the cyclotrimerization of di(2-thienyl)acetylenes proceeded smoothly to afford hexa(2-thienyl)benzenes.
Abruña +22 more
core +1 more source
The impact of natural product chemistry on medicine [PDF]
Pure and Applied Chemistry, 1967 Abstract
openaire +1 more source
Chemistry, 2017 The productive exploration of chemical space is an enduring challenge in chemical biology and medicinal chemistry. Natural products are biologically relevant, and their frameworks have facilitated chemical tool and drug discovery.
Daniel J. Foley +9 more
semanticscholar +1 more source
Production of antibacterial compounds by a Steely hybrid polyketide synthase in Dictyostelium
FEBS Open Bio, EarlyView.By selecting appropriate production species under optimised culture conditions, new chlorinated dibenzofuran compounds, which previously could not be analysed in sufficient quantities, were identified from cellular slime mould fruiting bodies. The strong antibacterial activity exhibited by these compounds suggests a link to the ecological function of ...
Tomoaki R. Yamashita +3 more
wiley +1 more source
Unification Achieved: William Cullen’s Theory of Heat and Phlogiston as an example of his Philosophical Chemistry [PDF]
, 2006 William Cullen, lecturer in chemistry at Glasgow and Edinburgh Universities, spent many years formulating his own theory of heat and combustion, the most developed version of which appears in a little-known set of lecture notes of 1765.
Taylor, G
core +1 more source
FEBS Open Bio, EarlyView.Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel +9 more
wiley +1 more source
Capturing Biological Activity in Natural Product Fragments by Chemical Synthesis
Angewandte Chemie, 2016 Natural products have had an immense influence on science and have directly led to the introduction of many drugs. Organic chemistry, and its unique ability to tailor natural products through synthesis, provides an extraordinary approach to unlock the ...
E. A. Crane, K. Gademann
semanticscholar +1 more source