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Marine Natural Product Bis-indole Alkaloid Caulerpin: Chemistry and Biology.
Mini-Reviews in Medical Chemistry, 2019Marine bis-indole alkaloids comprise a large and increasingly growing class of secondary metabolites, and continue to deliver a great variety of structural templates for diverse biological targets.
Jignesh Lunagariya +4 more
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Natural products – learning chemistry from plants
Biotechnology Journal, 2014AbstractPlant natural products (PNPs) are unique in that they represent a vast array of different structural features, ranging from relatively simple molecules to very complex ones. Given the fact that many plant secondary metabolites exhibit profound biological activity, they are frequently used as fragrances and flavors, medicines, as well as ...
Staniek, A. +8 more
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1987
Tricyclic compounds 756 and 757 have been found to exist in low concentration in lavender oil. Structure proof was realized by selenium dioxide oxidation of α-cedrene. Hydrogenation of 756 and subsequent copper-catalyzed oxidation of the saturated aldehyde furnished 757 [347].
Leo A. Paquette, Annette M. Doherty
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Tricyclic compounds 756 and 757 have been found to exist in low concentration in lavender oil. Structure proof was realized by selenium dioxide oxidation of α-cedrene. Hydrogenation of 756 and subsequent copper-catalyzed oxidation of the saturated aldehyde furnished 757 [347].
Leo A. Paquette, Annette M. Doherty
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Organic and biomolecular chemistry, 2019
Microorganisms are remarkable chemists, with enzymes as their tools for executing multi-step syntheses to yield myriad natural products. Microbial synthetic aptitudes are illustrated by the structurally diverse 2,5-diketopiperazine (DKP) family of ...
Paul Borgman, R. D. Lopez, Amy L. Lane
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Microorganisms are remarkable chemists, with enzymes as their tools for executing multi-step syntheses to yield myriad natural products. Microbial synthetic aptitudes are illustrated by the structurally diverse 2,5-diketopiperazine (DKP) family of ...
Paul Borgman, R. D. Lopez, Amy L. Lane
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Journal of Medicinal Chemistry, 2019
By forming extended hydrogen-bond networks, the contribution of hydroxyl groups to affinity can reach several orders of magnitude. However, because of the high directionality of their interactions, a maximal affinity gain can only be achieved when the ...
J. Cramer, C. P. Sager, B. Ernst
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By forming extended hydrogen-bond networks, the contribution of hydroxyl groups to affinity can reach several orders of magnitude. However, because of the high directionality of their interactions, a maximal affinity gain can only be achieved when the ...
J. Cramer, C. P. Sager, B. Ernst
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New chemistry from natural product biosynthesis
Biochemical Society Transactions, 2016Catalysts are a vital part of synthetic chemistry. However, there are still many important reactions for which catalysts have not been developed. The use of enzymes as biocatalysts for synthetic chemistry is growing in importance due to the drive towards sustainable methods for producing both bulk chemicals and high value compounds such as ...
Hubert, Catherine Bastienne Maider +1 more
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Marine Natural Products Chemistry
1977Field Observation - Prelude to Discovery of Marine Natural Products.- Recent Developments in Terpenoid and Steroid Chemistry of Alcyonacea.- Cembrane Derivatives from Sarcophytum glaucum.- The Chemistry of Some Opisthobranch Molluscs.- Constituents of the Hemichordate Ptychodera flava laysanica.- The Chemistry of Adenochrome (s).- A Survey of ...
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Flow chemistry syntheses of natural products
Chemical Society Reviews, 2013The development and application of continuous flow chemistry methods for synthesis is a rapidly growing area of research. In particular, natural products provide demanding challenges to this developing technology. This review highlights successes in the area with an emphasis on new opportunities and technological advances.
Julio C, Pastre +2 more
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Natural Product and Material Chemistries—Separated Forever?
Journal of the American Chemical Society, 2013Chemistry research is an eloquent, yet extremely complex discipline consisting of a diverse range of topics. The complexity of every sub-discipline requires extensive focus, which can limit cross-talk between fields, thus leading to their isolation. In particular, natural product and material chemistries have experienced this trend, and it has led to ...
Kunz, H., Müllen, K.
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Natural Products Chemistry III
1988Natural product chemistry has undergone an explosive growth during the latter half of the current century. This has been brought about by a number of factors. One of these has been the growing number of sub stances from natural sources which display interesting pharmacological activities. These include antibiotics, anti-tumor agents, immunostimu lants,
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