Results 141 to 150 of about 4,327,329 (308)

Enantioselective and Unifying Entry into Arcutane Natural Products

, 2023
Mario Gaviria
openalex   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source

Aerobic oxidative bromination and iodination enabled by alloxan and ascorbic acid to mimic flavin-dependent halogenases

Nature Communications
The fundamentally significant halogenation processes in organic synthesis heavily depend on the use of hazardous and toxic elemental halogens directly or indirectly, inevitably increasing environmental burden and leading to various production problems ...
Shiqi Zhang, Guang-xun Li, Dongmei Fang, Xia Zhang, Shangjing Chen, Xin Cui, Zhuo Tang   +6 more
doaj   +1 more source

Conversion of coal fly ash by-products into high-grade zeolite by a quasi natural crystallization process [PDF]

, 2022
Silviya Boycheva, Denitza Zgureva
openalex   +1 more source

Division of Natural Products Chemistry [PDF]

, 2004
この論文は国立情報学研究所の学術雑誌公開支援事業により電子化されまし
Banskota A.H., 手塚 康弘, 門田 重利   +2 more
core   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Natural products targeting autophagy and apoptosis in NSCLC: a novel therapeutic strategy [PDF]

Peiyi Qin, Qingchen Li, Qi Zu, Ruxue Dong, Yuanfu Qi   +4 more
openalex   +1 more source

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

FEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

In vitro and in silico anthelmintic and antibacterial activity of Rubus ellipticus leaf extracts

Discover Chemistry
Background Bacterial and helminthic evolution has resulted in a shocking development of antibiotic and anthelminthic resistance. Medicinal plants provide an encouraging source to develop new antibacterial and anthelmintic agents.
Deepak Kumar, Adarsh Kumar, Ankit Kumar Singh, Harshwardhan Singh, Pradeep Kumar   +4 more
doaj   +1 more source