Results 151 to 160 of about 12,894,217 (402)
FEBS Open Bio, EarlyView.Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel +9 more
wiley +1 more source
NutrientsA natural product is an organic compound from a living organism that can be isolated from natural sources or synthesized [...]
Joanna Bartkowiak-Wieczorek +1 more
openaire +2 more sources
Malaria Journal, 2018 Background Primaquine (PQ), an 8-aminoquinoline, is the only drug approved by the United States Food and Drug Administration for radical cure and prevention of relapse in Plasmodium vivax infections.
Bharathi Avula +13 more
doaj +1 more source
Vector diseases treatment based on intermediate complexion using textile substrates [PDF]
, 2019 The most efficient insect repellents are DEET (N, N-diethhyl-meta-toluamide) from synthetic origin and citronella essential oil from natural origin. However, there are other products that can also be used as insect repellents from synthetic origin, such ...
Lis Arias, Manuel José +2 more
core +1 more source
FEBS Open Bio, EarlyView.CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee +3 more
wiley +1 more source
Asymmetric total synthesis of alkaloid natural products without external chiral sources [PDF]
, 2018 The chirality of a starting material having a chiral sp3-carbon can be preserved under some circumstances in the reaction product even though the reaction proceeds at the chiral carbon as a reaction center through reactive intermediates.
Kim, Sanghee
core
A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms
FEBS Open Bio, EarlyView.We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley +1 more source
From fundamental insights to economic viability: recovering natural products from deodorizer distillates [PDF]
, 2017 C
Bouriakova, Alexandra +2 more
core +1 more source
Ionic Liquid Solutions as a Green Tool for the Extraction and Isolation of Natural Products [PDF]
, 2018 Jiao Xiao, Chen Gang, Ning Li
openalex +1 more source
HSP70 governs permeability and mechanotransduction in primary human endothelial cells
FEBS Open Bio, EarlyView.HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez +5 more
wiley +1 more source