Results 161 to 170 of about 37,948 (196)

Middle to Late Pleistocene landscape evolution and glacial dynamics in the Eastern Alps: the Gröbminger Mitterberg record, Austria

open access: yesBoreas, EarlyView.
Glacial erosion during the Last Glacial Maximum (LGM) has removed much evidence of earlier glaciations and interglacials in the European Alps. At Gröbminger Mitterberg (GM), beneath a blanket of LGM till, a distinctive sediment archive preserves deposits predating the LGM.
Gerit E. U. Griesmeier   +7 more
wiley   +1 more source

Tobacco plant as possible biomonitoring tool of red mud dust fallout and increased natural radioactivity. [PDF]

open access: yesHeliyon, 2020
Kovács T   +4 more
europepmc   +1 more source

Refining the timing of Middle Pleistocene (MIS 12 to MIS 6) ice advances into northern central Europe: sedimentological analysis and single‐grain luminescence dating of glaciotectonic complexes and tunnel‐valley fills

open access: yesBoreas, EarlyView.
We summarize the current state of knowledge on the age of the Middle Pleistocene ice advances into northern central Europe and provide 25 new single‐grain feldspar luminescence ages of Elsterian and Saalian glacigenic sediments to constrain the age of the ice advances and their tentative correlation with marine isotope stages/substages.
Niklas von Soest   +10 more
wiley   +1 more source

A PK/PD study on antihyperalgesia by an α2/3‐GABAA receptor PAM in mice: Lack of tolerance liability and potential involvement of γ1‐GABAA receptors

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose GABAA receptors (GABAARs) are heteropentameric ion channels that control almost all CNS functions, including spinal nociception. Most GABAARs contain a γ2 subunit but differ in their α and β subunit composition. TPA023B is an α2/α3 subtype selective, non‐sedative, positive allosteric modulator (PAM) with antihyperalgesic
Elena Neumann   +12 more
wiley   +1 more source

Intraocular Metastasis: Differential Diagnosis and Management

open access: yesClinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Intraocular metastases represent the most common type of malignant intraocular tumour in adults. These commonly affect the choroid but can also involve the iris, ciliary body, retina, vitreous, optic disc or lens. Breast and lung cancer are the most common origins of intraocular metastases.
Genovefa Μachairoudia   +3 more
wiley   +1 more source

Gestational Melatonin Supplementation Attenuates Maternal Sleep Deprivation‐Induced Steatohepatitis Susceptibility in Offspring

open access: yesCell Proliferation, EarlyView.
Maternal SD during pregnancy enhances the development of diet‐induced NASH in adult offspring of both sexes through an NR4A3‐dependent mechanism, characterised by heightened inflammation and increased apoptosis. Maternal melatonin supplementation effectively alleviates this increased susceptibility to NASH in offspring.
Fei Guo   +6 more
wiley   +1 more source

Examining the Role of Artificial Intelligence in Assessment: A Comparative Study of ChatGPT and Educator‐Generated Multiple‐Choice Questions in a Dental Exam

open access: yesEuropean Journal of Dental Education, EarlyView.
ABSTRACT Aim To compare the item difficulty and discriminative index of multiple‐choice questions (MCQs) generated by ChatGPT with those created by dental educators, based on the performance of dental students in a real exam setting. Materials and Methods A total of 40 MCQs—20 generated by ChatGPT 4.0 and 20 by dental educators—were developed based on ...
Nezaket Ezgi Özer   +4 more
wiley   +1 more source

Risk of Transformation to Acute Myeloid Leukaemia and Myelodysplastic Syndromes in Patients With Myeloproliferative Neoplasms Over Attained Age and Time Since Diagnosis: A Nationwide Cohort Study

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT Background Individuals with polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF) face transformation risks to acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS). While older age is linked to increased risk, it remains unclear whether risk increases with age or with disease duration.
Nurgul Batyrbekova   +5 more
wiley   +1 more source

Deciphering the properties and reaction mechanism of anhydromevalonate phosphate decarboxylase, a prenylated flavin mononucleotide‐dependent enzyme in the archaeal mevalonate pathway

open access: yesThe FEBS Journal, EarlyView.
Characterization of anhydromevalonate phosphate decarboxylase, the UbiD‐family decarboxylase involved in the archaeal mevalonate pathway, was conducted. The enzyme is responsible for the biosynthesis of isoprenoids, such as archaeal membrane lipids, respiratory quinones, and dolichols.
Rino Ishikawa   +9 more
wiley   +1 more source

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