Results 91 to 100 of about 10,832 (262)

A Fully Defined GelMA‐Based Matrix Allows Fine Tuning of Tissue‐Relevant Biomechanical and Biochemical Cues for Organoid Culture

Advanced Healthcare Materials, EarlyView.
A fully defined GelMA‐based ECM platform integrates tunable tissue‐relevant stiffness with laminin–entactin biochemical supplementation to support mouse small intestinal organoid growth. Coordinated control of mechanical and biochemical cues promotes robust proliferation, budding morphogenesis, differentiation, and passaging, providing a reproducible ...
Junyi Liu, Su Su Htwe, Lay Poh Tan, Yen Choo   +3 more
wiley   +1 more source

The outcomes of Quercus robur natural regeneration after clear-cutting in the north-eastern part of Ukraine

Folia Oecologica
Enabling natural seed regeneration is important because natural stands grown from seeds are more productive compared to vegetative and artificial ones; they are also more resistant to adverse environmental factors and climate change. The aim of the study
Tkach Viktor, Rumiantsev Maksym, Kobets Oleksii, Obolonyk Iryna   +3 more
doaj   +1 more source

Mechanically Compliant, Precision‐Porous Brain Implants Reduce the Foreign Body Reaction and Guide Regeneration

Advanced Healthcare Materials, EarlyView.
This study explores how the brain responds to implants of different properties. Hydrogels with various mechanical properties and pore sizes were implanted in adult rat brains. It is observed that hydrogels with mechanical property closely matched to the brain and 40 µm pore size elicit a pro‐healing response from the brain by modulating the immune ...
Ian Dryg, Le Zhen, Rebecca Darrow, Savannah Lawton, Lars Crawford, Robert Robinson, Steve Perlmutter, James D. Bryers, Buddy D. Ratner   +8 more
wiley   +1 more source

Brain‐Wide Neuroregenerative Gene Therapy Improves Cognition in a Mouse Model of Alzheimer's Disease

Advanced Science
Alzheimer's disease (AD) is a progressive and irreversible brain disorder with extensive neuronal loss in the neocortex and hippocampus. Current therapeutic interventions focus on the early stage of AD but lack effective treatment for the late stage of ...
Zheng Wu, Liang Xu, Yu Xie, Abhijeet Sambangi, Shreya Swaminathan, Zifei Pei, Wenyu Ji, Zeru Li, Yaowei Guo, Zhifei Li, Gong Chen   +10 more
doaj   +1 more source

Vascularization of Human iPSC‐Derived Kidney Organoids Using Perfusion Culture, Pre‐Vascularized Collagen Scaffolds, and Decellularized Extracellular Matrix

Advanced Healthcare Materials, EarlyView.
An integrated perfusion‐based culture platform combining pre‐vascularized collagen scaffolds, stromal vascular fraction cells, and kidney decellularized extracellular matrix promotes vascularization of human iPSC‐derived kidney organoids. The platform provides evidence of interactions between vascular networks and glomerular‐like structures and enables
Helen Kearney, Andrea Mazzoleni, Ivan Martin, Lorenzo Moroni, Manuele Giuseppe Muraro, Carlos Mota   +5 more
wiley   +1 more source

SURVIVAL AND NATURAL REGENERATION OF FOREST ESSENCES CULTIVATED IN ALTERED AREAS THIRTY-FIVE YEARS AFTER PLANTING

, 2022
Harley Araújo da Silva, Thiago Augusto da Cunha, Veronica Passos   +2 more
openalex   +2 more sources

Effect of Invasive Rhododendron ponticum L. on Natural Regeneration and Structure of Fagus orientalis Lipsky Forests in the Black Sea Region [PDF]

, 2020
Zdeněk Vacek, Stanislav Vacek, Derya Eşen, Oktay Yıldız, Jan Král, Josef Gallo   +5 more
openalex   +1 more source

MicroRNA-21a-5p-modified macrophage exosomes as natural nanocarriers promote bone regeneration by targeting GATA2 [PDF]

, 2023
Xin Luo, Chun-Xiu Meng, Yujue Zhang, Qicui Du, Cai-Yao Hou, Huifen Qiang, Kun Liu, Zhao-Yong Lv, Jun Li, Fengzhen Liu   +9 more
openalex   +1 more source

Dynamic Loading Regulates Meniscus‐Like Matrix Production in Human Mesenchymal Stromal Cell‐Seeded PET Scaffolds

Advanced Healthcare Materials, EarlyView.
Dynamic compression enhances mesenchymal stromal cell proliferation in nonwoven PET scaffolds under chondrogenic differentiation conditions and triggers mechanosensitive transcriptional programs associated with extracellular matrix remodeling. These findings highlight the potential of mechanically stimulated PET scaffolds as a promising platform for ...
Graciosa Quelhas Teixeira, Luisa de Roy, Anna‐Lotta Feldmeier, Mubashir Ahmad, Sofia Pilão, Maria Ahrens, Anita Ignatius, Carsten Linti, Andreas Martin Seitz   +8 more
wiley   +1 more source

Natural regeneration of cork oak forests under climate change: a case study in Portugal

Frontiers in Forests and Global Change
The sustainability of forest species is directly related to the success of stand regeneration. Assuring success is particularly critical in stands where perpetuity relies on natural regeneration, as is often the case with cork oak forests.
Stéphanie Ribeiro, Adelaide Cerveira, Paula Soares, Nuno Almeida Ribeiro, Constança Camilo-Alves, Teresa Fidalgo Fonseca, Teresa Fidalgo Fonseca, Teresa Fidalgo Fonseca   +7 more
doaj   +1 more source