Results 141 to 150 of about 5,231,604 (371)

Brain‐Wide Neuroregenerative Gene Therapy Improves Cognition in a Mouse Model of Alzheimer's Disease

Advanced Science
Alzheimer's disease (AD) is a progressive and irreversible brain disorder with extensive neuronal loss in the neocortex and hippocampus. Current therapeutic interventions focus on the early stage of AD but lack effective treatment for the late stage of ...
Zheng Wu, Liang Xu, Yu Xie, Abhijeet Sambangi, Shreya Swaminathan, Zifei Pei, Wenyu Ji, Zeru Li, Yaowei Guo, Zhifei Li, Gong Chen   +10 more
doaj   +1 more source

Florística da vegetação arbustivo - arbórea colonizadora de uma área degradada por mineração de caulim, em Brás Pires, MG Floristic of shrub - tree vegetation colonizing an area degraded by kaolin mining, in Brás Pires, MG

Revista Árvore, 2005
Este estudo teve como objetivos analisar a composição florística da vegetação arbustivo-arbórea colonizadora de uma área degradada por mineração de caulim, em Brás Pires, MG, compará-la com outros fragmentos florestais e caracterizar aspectos de auto ...
Fernanda Squizzatto de Araújo, Sebastião Venâncio Martins, João Augusto Alves Meira Neto, João Luiz Lani, Ismael Eleotério Pires   +4 more
doaj   +1 more source

Natural cardiac regeneration conserves native biaxial left ventricular biomechanics after myocardial infarction in neonatal rats

, 2022
Hanjay Wang, Andrew D. Wisneski, Annabel M. Imbrie-Moore, Michael J. Paulsen, Zhongjie Wang, Yue Xuan, Hector Lopez Hernandez, Camille E. Hironaka, Haley J. Lucian, Hye Sook Shin, Shreya Anilkumar, Akshara D. Thakore, Justin M. Farry, Anahita Eskandari, Kiah M. Williams, Frederick Grady, Matthew A. Wu, Jinsuh Jung, Lyndsay M. Stapleton, Amanda N. Steele, Yuanjia Zhu, Y. Joseph Woo   +21 more
openalex   +2 more sources

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source

Estudo do banco de sementes em povoamentos florestais puros e em uma capoeira de Floresta Ombrófila Aberta, no município de Areia, PB, Brasil Study of a seed bank in a pure forest population and a ombrophylous secondary forest in Areia Municipal district, PB, Brazil

Acta Botânica Brasílica, 2006
Em amostragem realizada na estação seca (outubro/2002) em três povoamentos florestais puros constituídos por: sabiá (Mimosa caesalpiniaefolia), sombreiro (Clitoria fairchildiana) e pinus (Pinus sp.) e em uma área em estágio inicial de sucessão ecológica "
Kilson Pinheiro Lopes, Vênia Camelo de Souza, Leonaldo Alves de Andrade, Genaro Viana Dornelas, Riselane de Lucena Alcântara Bruno   +4 more
doaj   +1 more source

Recent advances of natural and bioengineered extracellular vesicles and their application in vascular regeneration [PDF]

, 2022
Jianxiong Xu, Jinxuan Wang, Yidan Chen, Yuanfang Hou, Jianjun Hu, Guixue Wang   +5 more
openalex   +1 more source

Expanding Chemical Space of Nucleic Acid Nanoparticles for Tunable Antiviral‐Like Immunomodulatory Responses and Potent Adjuvant Activity

Advanced Functional Materials, EarlyView.
We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj, Hannah S. Newton, Jian Wang, Laxmi Pandey, Yelixza I. Avilla, Phong Nguyen, Morgan Chandler, Justin Halman, Yasmine Radwan, Stephanie Smith, Elijah Edmondson, Simone Difilippantonio, Chelsea Sanders, Bao Tran, Yongmei Zhao, Shaojun Xie, Edward Cedrone, Barry W. Neun, Meni Wanunu, Nikolay V. Dokholyan, Marina A. Dobrovolskaia, Kirill A. Afonin   +21 more
wiley   +1 more source

Tailoring the Properties of Functional Materials With N‐Oxides

Advanced Functional Materials, EarlyView.
The properties of materials bearing N‐oxide groups are often dominated by the polar N+─O− bond. It provides hydrophilicity, selective ion‐binding, electric conductivity, or antifouling properties. Many of the underlying mechanisms have only recently been discovered, and the interest in N‐oxide materials is rapidly growing.
Timo Friedrich, Michelle Kobus, Shirin Mesgarha, Erica Moretto, Laurens Grosche, Wolfgang Maison   +5 more
wiley   +1 more source

A Smart Bio‐Battery Facilitates Diabetic Bone Defect Repair Via Inducing Macrophage Reprogramming and Synergistically Modulating Bone Remodeling Coupling

Advanced Functional Materials, EarlyView.
This research presents a novel implantable bio‐battery, GF‐OsG, tailored for diabetic bone repair. GF‐OsG generates microcurrents in high‐glucose conditions to enhance vascularization, shift macrophages to the M2 phenotype, and regulate immune responses.
Nanning Lv, Haifu Sun, Wenxiang Tang, Yonggang Li, Zhonglai Qian, Lihui Hong, Chong Chen, Hongye Li, Jiaxiang Bai, Yusen Qiao, Mingming Liu   +10 more
wiley   +1 more source

The outcomes of Quercus robur natural regeneration after clear-cutting in the north-eastern part of Ukraine

Folia Oecologica
Enabling natural seed regeneration is important because natural stands grown from seeds are more productive compared to vegetative and artificial ones; they are also more resistant to adverse environmental factors and climate change. The aim of the study
Tkach Viktor, Rumiantsev Maksym, Kobets Oleksii, Obolonyk Iryna   +3 more
doaj   +1 more source