Results 31 to 40 of about 2,782,219 (332)

Evaluation of Soil Physicochemical Properties Under Different Soil Conservation Techniques Across Slope Gradients in Northwestern Ethiopia

Applied and Environmental Soil Science
Soil degradation, marked by erosion, nutrient depletion, and organic matter loss, is a significant challenge to agricultural productivity and environmental sustainability globally.
Fekadu Debebe, Wondwosson Kibrie, Habtamu Admas, Beletech Kindu, Dessalegn Birhanu   +4 more
doaj   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Optimal Exploitation of a General Renewable Natural Resource under State and Delay Constraints

Mathematics, 2020
In this work, we study an optimization problem arising in the management of a natural resource over an infinite time horizon. The resource is assumed to evolve according to a logistic stochastic differential equation.
M’hamed Gaïgi, Idris Kharroubi, Thomas Lim   +2 more
doaj   +1 more source

Fewer bat passes are detected during small, commercial drone flights

Scientific Reports, 2021
Advances in technological capabilities, operational simplicity and cost efficiency have promoted the rapid integration of unmanned aerial vehicles (UAVs) into ecological research, providing access to study taxa that are otherwise difficult to survey ...
Gabrielle Ednie, David M. Bird, Kyle H. Elliott   +2 more
doaj   +1 more source

Digital Preservation and Access of Natural Resources Documents [PDF]

, 2017
Digitization and preservation of natural resource documents were reviewed and the current status of digitization presented for a North American university.
Bullard, Steven H, Kulhavy, David, McBroom, Matthew W, Reynolds, R Philip, Unger, Daniel   +4 more
core   +2 more sources

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Gut microbiome is affected by inter-sexual and inter-seasonal variation in diet for thick-billed murres (Uria lomvia)

Scientific Reports, 2021
The role of the gut microbiome is increasingly being recognized by health scientists and veterinarians, yet its role in wild animals remains understudied.
Esteban Góngora, Kyle H. Elliott, Lyle Whyte   +2 more
doaj   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Chloroform Fraction of Mitracarpus hirtus Induces p53-Mediated Cell Cycle Arrest and Apoptosis in MCF-7 Breast Cancer Cells [PDF]

Pharmaceutical Sciences
Background: Breast cancer remains a serious life-threatening disease to women worldwide, contributing to a high rate of mortality among women. A critical molecular event implicated in breast cancer progression is the dysregulation of the tumour ...
Ibrahim Malami, Ramlatu Yusuf Hussaini, Zakiyyah Yakubu Yahaya Ibrahim, Ibrahim Babangida Abubakar, Aliyu Muhammad   +4 more
doaj   +1 more source