Results 101 to 110 of about 2,549,299 (308)

From Natural Resources to Natural Assets [PDF]

open access: yes
This article examines the scope for strategies to build natural assets in the hands of low-income individuals and communities. Natural assets include sources of raw materials such as forests and fisheries, and the airsheds, lands, and water bodies that ...
James Boyce
core  

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

Comparative analysis of national approaches on voluntary copyright relinquishment [PDF]

open access: yes, 2014
The report considers first the question of how copyright is justified, as this may have some bearing on whether a country will allow an author to make a voluntary statement leading to the expiration of his/her rights.
Guadamuz, Andres
core  

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

The History and Practice of Substantive Due Process: A Question of Legitimacy

open access: yesTrento Student Law Review, 2019
While the concept of substantive due process can be found in judicial decision-making prior to the Civil War, in the 1960s it became and has remained a lightning rod among the juristic community.
James Marmaduke
doaj  

Culture and Learning [PDF]

open access: yes, 2010
Ensuring "the development of the child ... to the maximum extent possible" is part of every child’s rights under the UN Convention on the Rights of the Child.

core  

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

Towards an Analytical Framework for Assessing Property Rights to Natural Resources: A Case Study in the Communal Areas of Zimbabwe [PDF]

open access: yes
A taxonomy for describing property rights to natural resources is described and applied in a Zimbabwean case study. The taxonomy allows: tenures to be systematically compared and contrasted; incentives for natural resource management to be identified ...
Kundhlande, Godfrey, Luckert, Martin K.
core   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

open access: yesAging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss   +12 more
wiley   +1 more source

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