Results 81 to 90 of about 5,946,843 (301)

A Critical Study of the Convention on the Elimination of All Forms of Discrimination Against Women: A Proposal for an Islamic Model [PDF]

open access: yesFaṣlnāmah-i Pizhūhish-i Huqūq-i ̒Umūmī
IntroductionProtecting women’s rights has been a perennial concern of human rights advocates over the past two centuries. Their dedicated efforts have resulted in the recognition of gender equality in key human rights documents such as the Charter of the
Hojatollah Mansouri   +3 more
doaj   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

Children's natural rights in the law on mother and child welfare according to Montesquieu

open access: yesJournal of Social Sciences
This study focuses on Article 12 paragraph (1) letter g of Law No. 4-2024, Indonesia. This article states that "every mother and father has the obligation to instill religious values, faith in God Almighty, and good character in their children." The ...
MICHAEL, Tomy
doaj   +1 more source

Hobbes' account of life in the state of nature and its implications [PDF]

open access: yesSrpska Politička Misao
In an infamous paragraph in his magnum opus, Leviathan, Thomas Hobbes describes what he perceives to be the miserable condition of humankind in the state of nature, concluding that human life in this state is "solitary, poor, nasty, brutish, and short ...
Matić Ivan
doaj   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

open access: yesFEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão   +3 more
wiley   +1 more source

Toxocariasis: Current State of the Russian Federation Message 1: Risk of Toxocariasis Infection of the Population on the Territory of the Russian Federation

open access: yesЭпидемиология и вакцинопрофилактика, 2015
Data of Federal Service on Customers’ Rights Protection and Human Well-Being Surveillance State reports for the administrative eareas in 2010 - 2012 on sanitary-epidemiological well being of the population were analyzed, as well as information from the ...
O. Yu. Starostina   +2 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Аssessment of the Effectiveness of Etiotropic Prophylaxis of Tick-Borne Infections: the Systematization of concepts and methodological features

open access: yesЭпидемиология и вакцинопрофилактика, 2019
This review analyzes the methodological reasons for the heterogeneity of the results of the evaluation of the epidemiological effectiveness of vaccine prophylaxis of tick-borne encephalitis (TBE) using indicators such as the efficiency coefficient (COEF)
N. A. Penyevskaya, N. V. Rudakov
doaj   +1 more source

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