Results 51 to 60 of about 2,549,299 (308)

Can Natural Law Thinking be Made Credible in our Contemporary Context? [PDF]

open access: yes, 2010
One of the best-known members of the United Nations Commission which drafted the 1948 "Universal Declaration of Human Rights," Jacques Maritain, famously held that the "natural rights" or "human rights" possessed by every human being are grounded and ...
Baur, Michael
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Hobbes' account of life in the state of nature and its implications [PDF]

open access: yesSrpska Politička Misao
In an infamous paragraph in his magnum opus, Leviathan, Thomas Hobbes describes what he perceives to be the miserable condition of humankind in the state of nature, concluding that human life in this state is "solitary, poor, nasty, brutish, and short ...
Matić Ivan
doaj   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

The Claims of Animals and the Needs of Strangers: Two Cases of Imperfect Right [PDF]

open access: yes, 2018
This paper argues for a conception of the natural rights of non-human animals grounded in Kant’s explanation of the foundation of human rights. The rights in question are rights that are in the first instance held against humanity collectively speaking ...
Korsgaard, Christine M.
core  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

The Nature of Rights [PDF]

open access: yesPhilosophy & Public Affairs, 2005
The twentieth century saw a vigorous debate over the nature of rights.\ud Will theorists argued that the function of rights is to allocate domains of\ud freedom. Interest theorists portrayed rights as defenders of well-being.\ud Each side declared its conceptual analysis to be closer to an ordinary\ud understanding of what rights there are, and to an ...
openaire   +6 more sources

HUMAN RIGHTS AS NATURAL RIGHTS

open access: yesInternational Journal of Advanced Research, 2021
The concept of human rights has always been a burning and one of the most significant concepts in the field of Social Sciences and Humanities. Human rights are the basic and birth rights of every individual. These individualistic rights are important in order to lead a dignified life in society.
openaire   +1 more source

The Language of Rights: Towards an Aristotelian-Thomistic Analysis [PDF]

open access: yes, 2010
Alasdair MacIntyre has argued that our contemporary discourse about “rights,” and “natural rights” or “human rights,” is alien to the thought of Aristotleand Aquinas.
Baur, Michael
core  

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

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