Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes
ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin +8 more
wiley +1 more source
The impacts of mesoscale eddies on the modulation of typhoon-induced oceanic responses are important for understanding ocean dynamics. Satellite observations identified prominent ocean surface temperature and chlorophyll changes over the regions with ...
Weifang Jin +8 more
doaj +1 more source
Corrigendum to "Dynamics in mangroves assessed by high-resolution and multi-temporal satellite data: a case study in Zhanjiang Mangrove National Nature Reserve (ZMNNR), P. R. China" published in Biogeosciences, 10, 5681–5689, 2013 [PDF]
K. Leempoel +7 more
openaire +3 more sources
Myostatin/Smad3 in Spinal Muscular Atrophy: Biomarkers of Disease Severity and Treatment Response
ABSTRACT Objective Given the role of Myostatin (MSTN) in muscle homeostasis and its modulation by current spinal muscular atrophy (SMA) therapies, we investigated serum MSTN and, for the first time, its downstream effector Smad3 as candidate non‐invasive biomarkers in SMA patients undergoing disease‐modifying therapies (DMTs).
Giorgia Riolo +11 more
wiley +1 more source
Scandium (Sc)‐doped AlCoCrFeMo HEA coatings are fabricated via flame spraying with 0.1, 0.3, and 0.5 wt% Sc additions. Among these, the HEA‐Sc0.3 coating exhibits the highest corrosion resistance, indicated by a more positive corrosion potential and lower current density.
Pankaj Kumar +7 more
wiley +1 more source
Predicting the 2023/24 El Niño from a multi-scale and global perspective
The 2023/24 El Niño ranks as the second strongest event in the twenty-first century thus far. The event exhibited a two-step warming tendency and two warming centers, which could not be explained by the heat content buildup.
Ruikun Hu +6 more
doaj +1 more source
Impact of MgO Additions on the Oxidation Resistance and Compression Behavior of Vanadium Alloys
An increase in oxidation resistance at 600 °C is achieved for alloys containing more than 2.5 wt.% MgO. It has been established that, along with V2O5, MgO6V2, and Mg2O7V2 are formed, which are presumed to enhance oxidative stability. Furthermore, the possible transformation of Mg‐vanadates through reaction with CO2, which presumably occurs in this ...
Ievgen Solodkyi +5 more
wiley +1 more source
The rapid expansion of seaweed aquaculture has profound impacts on coastal ecosystems, yet the lack of long-term, high-precision spatiotemporal monitoring methods has constrained systematic understanding of aquaculture dynamics and their environmental ...
Bozhong Zhu +9 more
doaj +1 more source
Experimental Study on Bottom-Up Detection of Underwater Targets Based on Polarization Imaging
Previous studies on the polarization imaging of underwater targets mainly focused on top-down detection; however, the capacities of bottom-up detection were poorly known.
Tianfeng Pan +6 more
doaj +1 more source
Investigating the Low‐Temperature Phase Stability of the Binary Ta–W System
Atomistic simulations show that the binary Ta–W system forms ordered intermetallic phases, B2‐TaW and D03‐TaW3, as 0 K ground states. Configurational entropy, however, lowers the free energy of the disordered bcc solid solution, which becomes the stable phase above about 400 K.
Klemens Lechner +7 more
wiley +1 more source

