Results 121 to 130 of about 12,501,152 (388)

Multicenter study for CH-VAD as a fully magnetically levitated left ventricular assist device

open access: yesiScience
Summary: The CH-VAD is a fully magnetically levitated left ventricular assist device (LVAD) designed for optimized hemocompatibility. This study evaluates the clinical outcomes of 77 patients implanted with the CH-VAD across seven centers in China from ...
Yifan Lu   +12 more
doaj  

Mitogenomic exploration supports the historical hypothesis of anthropogenic diffusion of a zoonotic parasite Echinococcus multilocularis

open access: yesiScience, 2023
Summary: Animal movement across regions owing to human activity can lead to the introduction of pathogens, resulting in disease epidemics with medical and socioeconomic significance.
Naoki Hayashi   +11 more
doaj  

Scientific research in the natural sciences in South Africa: A scientometric study

open access: yes, 2013
As a leading producer of scientific publications on the African continent, South Africa has made remarkable progress. However, attempts are yet to be made to comprehend the empirical reality of scientific production in South Africa. One way to do this is
R. Sooryamoorthy
semanticscholar   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini   +10 more
wiley   +1 more source

Layer-by-layer coated probiotics with tannic acid-Ca2+ and casein phosphopeptide complexes for caries prevention and enamel remineralization

open access: yesiScience
Summary: Dental caries is a common disease resulting from tooth demineralization caused by bacterial plaque. Probiotics have shown great potential against caries by regulating the balance of oral flora.
Ming-Xin Cao   +7 more
doaj  

Sex difference in liver diseases: How preclinical models help to dissect the sex-related mechanisms sustaining NAFLD and hepatocellular carcinoma

open access: yesiScience, 2023
Summary: Only a few preclinical findings are confirmed in the clinic, posing a critical issue for clinical development. Therefore, identifying the best preclinical models can help to dissect molecular and mechanistic insights into liver disease ...
Alfredo Smiriglia   +5 more
doaj  

On The Theoretical Problematic of Arabic Physical Science Or Why Did Arabic Science Fail To Achieve The Copernican Revolution? [PDF]

open access: yesarXiv, 2012
A Hegelian version of the concept of problematic is used to investigate the underlying theoretical unity and structure of Arabic physical science (physics, astronomy and chemistry). A contradictory triad (associated with Platonism, Aristotelian philosophy and Ptolemaic science) is identified at the heart of the Arabic project for physical science.
arxiv  

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu   +15 more
wiley   +1 more source

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