Results 101 to 110 of about 16,943,207 (295)

Flexible terahertz beam manipulation and convolution operations in light-controllable digital coding metasurfaces

open access: yesiScience
Summary: The development of coding metasurface opens an important development direction for beam modulator components. However, the lack of dynamic tunability is a major obstacle to the development and practicality of terahertz coding metasurface.
Min Jia   +4 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

The Journal of Natural Sciences 1966

open access: yes, 1966
Issue of The Journal of Natural Sciences, a collaborative yearly publication (1962-1968) of the University of Scranton Chemistry, Biology, Physics, Mathematics, and Engineering ...
University of Scranton
core   +1 more source

Dishevelled localization and function are differentially regulated by structurally distinct sterols

open access: yesiScience
Summary: The Dishevelled (DVL) protein family forms supramolecular protein and lipid complexes at the cytoplasmic interface of the plasma membrane to regulate tissue patterning, proliferation, cell polarity, and DVL-dependent signaling, such as Wnt/β ...
Sonali Sengupta   +5 more
doaj   +1 more source

Toward More Inclusive Metrics and Open Science to Measure Research Assessment in Earth and Natural Sciences. [PDF]

open access: yesFront Res Metr Anal, 2022
Pourret O   +4 more
europepmc   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

open access: yesFEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay   +2 more
wiley   +1 more source

IFN-γ licenses normal and pathogenic ALPK1/TIFA pathway in human monocytes

open access: yesiScience
Summary: Alpha-kinase 1 (ALPK1) is an immune receptor sensing the bacterial nucleotide sugar ADP-heptose. ALPK1 phosphorylates TIFA leading to its oligomerization and downstream NF-κB activation.
Amandine Martin   +10 more
doaj   +1 more source

The Journal of Natural Sciences 1964

open access: yes, 1964
Issue of The Journal of Natural Sciences, a collaborative yearly publication (1962-1968) of the University of Scranton Chemistry, Biology, Physics, Mathematics, and Engineering ...
University of Scranton
core   +1 more source

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

open access: yesFEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson   +2 more
wiley   +1 more source

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