Results 81 to 90 of about 16,943,207 (295)

Soft wearable thermo+touch haptic interface for virtual reality

open access: yesiScience
Summary: Touch is an inherent source of tactile sensation in everyday life, followed by vision and audition. For rich tactile feedback, multimodal haptic feedback is necessary because a single touch simultaneously excites multiple types of tactile ...
Seohu Lee, Seongkwan Jang, Youngsu Cha
doaj   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

Negative regulation of lymphangiogenesis by Tenascin-C delays the resolution of inflammation

open access: yesiScience
Summary: Lymphatic vessels are required for the clearance of excess fluid and immune cells from inflamed tissue, making the regulation of lymphangiogenesis an important area of research.
Daisuke Katoh   +11 more
doaj   +1 more source

The natural selection of conservative science [PDF]

open access: yesStudies in History and Philosophy of Science Part A, 2019
Social epistemologists have argued that high risk, high reward science has an important role to play in scientific communities. Recently, though, it has also been argued that various scientific fields seem to be trending towards conservatism -- the increasing production of what Kuhn (1970) would have called `normal science'.
openaire   +6 more sources

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Enhanced global extreme droughts driven by the Indian Ocean and Pacific Ocean on decadal timescales

open access: yesiScience
Summary: In the 21st century, two record-breaking years of extreme drought coverage swept across the globe. These resulted in billions of agriculture losses and led to hunger and poverty in those developing countries.
Yihui Xu   +4 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

A human-system integration framework and its application for special vehicle interface design under typical human readiness levels

open access: yesiScience
Summary: Life cycle Human System Integration (HSI) practices are crucial for optimizing human system performance, reducing costs, and ensuring safety. To address the limited HSI practices under typical Human Readiness Levels (HRLs), our study proposes an
Chuanyan Feng   +4 more
doaj   +1 more source

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